Fonzi L, Belli M, Sonderegger R, Kaitsas V, Santacroce C, Passagrilli G
Bull Group Int Rech Sci Stomatol Odontol. 1989 Dec;32(3):157-61.
Biochemical variations of adenine and pyridine compounds in human gingival grafts during the period between excision and implantation have been studied. These groups of compounds are considered as "indicators" of the metabolic and energetic status of the living cells. Adenylic compounds such as ATP, ADP and AMP are involved in numerous metabolic processes as "modulators" of allosteric enzymes. NAD+ and NADP+ are involved in the carbohydrate metabolism as co-factors of many reactions of oxydoreduction. The exposure to air of the gingival tissue induces modifications in the energy state of the cells as well as in the ox-reox system. No variation is detectable in the intermediates of the pyridine compounds cycle.
对人牙龈移植物在切除和植入期间腺嘌呤和吡啶化合物的生化变化进行了研究。这些化合物组被视为活细胞代谢和能量状态的“指标”。腺苷酸化合物如ATP、ADP和AMP作为变构酶的“调节剂”参与众多代谢过程。NAD+和NADP+作为许多氧化还原反应的辅助因子参与碳水化合物代谢。牙龈组织暴露于空气中会导致细胞能量状态以及氧化还原系统发生改变。吡啶化合物循环的中间产物未检测到变化。
