Barvencik F, Amling M
Institut für Osteologie und Biomechanik, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland.
Orthopade. 2015 Sep;44(9):686-694. doi: 10.1007/s00132-015-3135-7.
Bone health is a crucial requirement for individual mobility. Preventive, diagnostic, and therapeutic actions to preserve or restore bone health are major tasks for orthopedic surgeons and health practitioners in musculoskeletal medicine.
In the context of the widespread vitamin D deficiency in Germany, it is relevant to keep in mind thatserum calcitriol levels above > 30 µg/l are necessary for optimal bone metabolism and bone health. In particular, because vitamin D deficiency not only increases the amount of non-mineralized bone matrix (osteoid), but it can also cause negative changes in the mineralized bone tissue. Widening of the osteons and osteocyte lacunae, together with increased bone aging under the osteoid layer, can lead to reduced fracture resistance.
Integration of bone metabolism into the orthopedic strategy is an important concept for optimizing treatment in modern musculoskeletal medicine.
骨骼健康是个体活动能力的关键要求。采取预防、诊断和治疗措施来维持或恢复骨骼健康是骨科医生和肌肉骨骼医学领域的健康从业者的主要任务。
鉴于德国普遍存在维生素D缺乏的情况，需要牢记血清骨化三醇水平高于30μg/l对于最佳骨代谢和骨骼健康是必要的。特别是，因为维生素D缺乏不仅会增加未矿化骨基质（类骨质）的量，还会导致矿化骨组织发生负面变化。骨单位和骨细胞陷窝增宽，以及类骨质层下骨老化加剧，可导致骨折抵抗力降低。
将骨代谢纳入骨科治疗策略是现代肌肉骨骼医学中优化治疗的重要理念。
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