Sicińska Paulina, Pytel Edyta, Kurowska Joanna, Koter-Michalak Maria
Katedra Biofizyki Skażeń Środowiska, Uniwersytet Łódzki.
Postepy Hig Med Dosw (Online). 2015 Jul 24;69:838-52. doi: 10.5604/17322693.1162673.
For some decades, an increase in propagation of coronary heart disease, obesity, diabetes, tumors and mental disorders has been observed. Consequently, new and effective methods of treatment of these diseases using drugs and diet supplements have been developed. A promising solution is the use of polyunsaturated fatty acids in the treatment of some diseases. These compounds have broad application in prevention of many diseases and are used to support standard therapies. Their activity is connected with participation in metabolic processes regulating biochemical transformations in cells and tissues. Omega-3 fatty acids regulate production of cytokines, increased levels of which may contribute to occurrence of chronic inflammatory diseases, autoaggression of the immunological system, arteriosclerosis or tumor development. These substances exert a beneficial effect on the blood system by improvement of blood circulation and nerve signal transmission. Omega-3 fatty acids reduce the risk of irregular heartbeat, stabilize arterial pressure, and restore balance in cholesterol metabolism disorders. They also play a key role in maintaining physical and mental efficiency; thus administration of these compounds for young children is of great importance. Nevertheless, administration of omega-3 fatty acids in the diet seems to be essential. The purpose of this study is to present the structure and sources of omega-3 and - 6 fatty acids and discuss the problems concerning therapeutic use of these compounds in various disorders.
几十年来，人们观察到冠心病、肥胖症、糖尿病、肿瘤和精神障碍的发病率有所上升。因此，已经开发出了使用药物和膳食补充剂治疗这些疾病的新的有效方法。一个有前景的解决方案是使用多不饱和脂肪酸治疗某些疾病。这些化合物在预防多种疾病方面有广泛应用，并用于支持标准疗法。它们的活性与参与调节细胞和组织中生化转化的代谢过程有关。欧米伽-3脂肪酸调节细胞因子的产生，细胞因子水平升高可能导致慢性炎症性疾病、免疫系统的自身攻击、动脉硬化或肿瘤发展。这些物质通过改善血液循环和神经信号传递对血液系统产生有益影响。欧米伽-3脂肪酸降低心律失常的风险，稳定动脉血压，并恢复胆固醇代谢紊乱的平衡。它们在维持身体和精神效能方面也起着关键作用；因此，给幼儿服用这些化合物非常重要。然而，在饮食中摄入欧米伽-3脂肪酸似乎至关重要。本研究的目的是介绍欧米伽-3和欧米伽-6脂肪酸的结构和来源，并讨论在各种疾病中治疗性使用这些化合物的相关问题。
