Gurnani Muskaan, Birken Catherine, Hamilton Jill
Division of Endocrinology, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada.
Division of Paediatric Medicine, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada.
Pediatr Clin North Am. 2015 Aug;62(4):821-40. doi: 10.1016/j.pcl.2015.04.001. Epub 2015 May 23.
One-third of North American children are overweight or obese. Pathologic obesity accounts for only a small percentage of these cases. The vast majority are the result of a complex interaction of genetic and hormonal, nutritional, physical activity, and physical and social environmental factors. Obesity increases the risk for various cardiometabolic, pulmonary, and psychosocial complications for children, which often continues into adulthood. Multidisciplinary care, focusing on family-centered behavior change, is an evidence-based, essential part of the treatment, along with pharmacologic and surgical options for more complex cases. Prevention and early intervention strategies are key to reversing the obesity epidemic.
三分之一的北美儿童超重或肥胖。病理性肥胖仅占这些病例的一小部分。绝大多数是遗传、激素、营养、身体活动以及身体和社会环境因素复杂相互作用的结果。肥胖会增加儿童出现各种心脏代谢、肺部和心理社会并发症的风险,这些并发症往往会持续到成年期。以家庭为中心的行为改变为重点的多学科护理是治疗的循证关键组成部分,对于更复杂的病例还可采用药物和手术治疗方案。预防和早期干预策略是扭转肥胖流行趋势的关键。