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危险单次饮酒和饮酒量与酒精使用障碍的独立及联合关联:来自瑞士年轻男性样本的证据。

Independent and combined associations of risky single-occasion drinking and drinking volume with alcohol use disorder: Evidence from a sample of young Swiss men.

作者信息

Baggio Stéphanie, Dupuis Marc, Iglesias Katia, Daeppen Jean-Bernard

机构信息

Life Course and Social Inequality Research Centre, University of Lausanne, Geopolis Building, CH-1015 Lausanne, Switzerland.

Institute of Psychology, University of Lausanne, Geopolis Building, CH-1015 Lausanne, Switzerland.

出版信息

Drug Alcohol Depend. 2015 Sep 1;154:260-3. doi: 10.1016/j.drugalcdep.2015.07.008. Epub 2015 Jul 15.

Abstract

BACKGROUND

Risky single-occasion drinking (RSOD) is a prevalent and potentially harmful alcohol use pattern associated with increased alcohol use disorder (AUD). However, RSOD is commonly associated with a higher level of alcohol intake, and most studies have not controlled for drinking volume (DV). Thus, it is unclear whether the findings provide information about RSOD or DV. This study sought to investigate the independent and combined effects of RSOD and DV on AUD.

METHODS

Data were collected in the longitudinal Cohort Study on Substance Use Risk Factors (C-SURF) among 5598 young Swiss male alcohol users in their early twenties. Assessment included DV, RSOD, and AUD at two time points. Generalized linear models for binomial distributions provided evidence regarding associations of DV, RSOD, and their interaction.

RESULTS

DV, RSOD, and their interaction were significantly related to the number of AUD criteria. The slope of the interaction was steeper for non/rare RSOD than for frequent RSOD.

CONCLUSIONS

RSOD appears to be a harmful pattern of drinking, associated with increased AUD and it moderated the relationship between DV and AUD. This study highlighted the importance of taking drinking patterns into account, for both research and public health planning, since RSO drinkers constitute a vulnerable subgroup for AUD.

摘要

背景

危险的单次饮酒(RSOD)是一种普遍且潜在有害的饮酒模式,与酒精使用障碍(AUD)增加有关。然而,RSOD通常与较高的酒精摄入量相关,并且大多数研究未对饮酒量(DV)进行控制。因此,尚不清楚这些研究结果是提供了关于RSOD还是DV的信息。本研究旨在调查RSOD和DV对AUD的独立和综合影响。

方法

在纵向物质使用风险因素队列研究(C-SURF)中收集了5598名20岁出头的瑞士年轻男性饮酒者的数据。评估包括两个时间点的DV、RSOD和AUD。二项分布的广义线性模型提供了关于DV、RSOD及其相互作用关联的证据。

结果

DV、RSOD及其相互作用与AUD标准数量显著相关。非/罕见RSOD的相互作用斜率比频繁RSOD的更陡。

结论

RSOD似乎是一种有害的饮酒模式,与AUD增加相关,并且它调节了DV与AUD之间的关系。本研究强调了在研究和公共卫生规划中考虑饮酒模式的重要性,因为RSOD饮酒者构成了AUD的一个脆弱亚组。

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