Addiction Medicine, Lausanne University Hospital CHUV, Rue du Bugnon, Lausanne, Switzerland.
Addiction Switzerland, Lausanne, Switzerland.
PLoS One. 2020 Jan 27;15(1):e0220232. doi: 10.1371/journal.pone.0220232. eCollection 2020.
(A) OBJECTIVE: This study aimed to identify trajectories of alcohol use (AU) and their associations with the development of alcohol use disorder (AUD) among young men with different weekly drinking patterns.
(B) METHOD: A longitudinal latent class analysis integrating several aspects of AU, such as drinking quantity and frequency on weekends vs workweek days, involving 4719 young Swiss men at ages 20, 21, and 25, and collected by the Cohort Study on Substance Use Risk Factors, was used to identify different AU trajectories over time. The development of AUD scores in these trajectories was investigated using generalized linear mixed models.
(C) RESULTS: Six AU trajectory classes, similar to those described in the literature, were identified: 'abstainers-light drinkers', 'light workweek increasers', 'light decreasers', 'moderate weekend decreasers', 'moderate workweek increasers', and 'heavy drinkers'. Only 12% of participants were assigned to a trajectory class with decreasing AU associated with a decline in their AUD score. AUD scores increased in trajectory classes exhibiting increasing AU on workweek days, despite low and moderate general AU. Finally, more than 59% of participants were on an AU trajectory presenting no change in their mean AUD score over time.
(D) CONCLUSIONS: Maturing out of problematic AU in emerging adulthood is not the norm in Switzerland, and the AUD score developed in late adolescence remains until at least emerging adulthood. AU on workweek days is a more practical marker of potentially problematic AU. This calls for timely interventions in adolescence and concerning regular drinking on workweek days in emerging adulthood.
(A) 目的:本研究旨在识别不同周饮酒模式的年轻男性中酒精使用(AU)轨迹及其与酒精使用障碍(AUD)发展的关系。
(B) 方法:一项纵向潜在类别分析整合了 AU 的多个方面,例如周末和工作日的饮酒量和频率,涉及 4719 名 20、21 和 25 岁的瑞士年轻男性,由物质使用风险因素队列研究收集,用于识别随时间变化的不同 AU 轨迹。使用广义线性混合模型研究这些轨迹中 AUD 评分的发展。
(C) 结果:确定了六个 AU 轨迹类别,类似于文献中描述的那些:“禁欲者-轻度饮酒者”、“轻度工作日增加者”、“轻度减少者”、“中度周末减少者”、“中度工作日增加者”和“重度饮酒者”。只有 12%的参与者被分配到与 AUD 评分下降相关的 AU 减少的轨迹类别。尽管 AU 总体较低且中度,但 AUD 评分在工作日 AU 增加的轨迹类别中增加。最后,超过 59%的参与者处于 AU 轨迹上,其平均 AUD 评分在整个时间内没有变化。
(D) 结论:在瑞士,成年初显期内从有问题的 AU 中成熟并非常态,青春期晚期发展的 AUD 评分至少持续到成年初显期。工作日的 AU 是潜在有问题的 AU 的更实用标记。这需要在青春期及时进行干预,并关注成年初显期工作日的有规律饮酒。