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不同头位侧卧位对开角型青光眼治疗患者眼压的影响

Effect of Different Head Positions in Lateral Decubitus Posture on Intraocular Pressure in Treated Patients With Open-Angle Glaucoma.

作者信息

Lee Tae-Eun, Yoo Chungkwon, Lin Shan C, Kim Yong Yeon

机构信息

Department of Ophthalmology, Korea University College of Medicine, Seoul, South Korea.

Department of Ophthalmology, Korea University College of Medicine, Seoul, South Korea.

出版信息

Am J Ophthalmol. 2015 Nov;160(5):929-936.e4. doi: 10.1016/j.ajo.2015.07.030. Epub 2015 Jul 23.

Abstract

PURPOSE

To investigate the effects of different head positions in the lateral decubitus posture on intraocular pressure (IOP) in medically treated patients with open-angle glaucoma (OAG).

DESIGN

Prospective observational study.

METHODS

setting: Institutional.

PARTICIPANTS

Twenty patients with bilateral OAG who received only latanoprost as treatment.

OBSERVATION PROCEDURES

IOP was measured using an ICare Pro tonometer in the sitting, supine, right, and left lateral decubitus posture. In lateral decubitus posture, IOP measurements were taken with 3 different head positions (30 degrees higher than, 30 degrees lower than, and parallel to the center of the thoracic vertebra) in a randomized sequence.

MAIN OUTCOME MEASURES

Comparison of the IOPs between the dependent (lower-sided) and nondependent eyes in the lateral decubitus postures with different head positions. We also analyzed the differences in IOPs between the better and worse eyes.

RESULTS

IOP was higher in the dependent eyes than in the nondependent eyes in lateral decubitus posture, regardless of the head position (all P < .05). Lower head position increased the IOP of dependent eyes, compared with the neutral or higher head position. However, the amounts of IOP elevation seen during the changes of body posture or head position were not significantly different between the better and worse eyes.

CONCLUSIONS

Low head position elevates IOP of the dependent eyes of medically treated OAG patients compared with neutral head position in the lateral decubitus posture. Adjustment of the height of a pillow may help mitigate IOP elevations resulting from lying on the side with a low or no pillow in glaucoma patients.

摘要

目的

探讨外侧卧位时不同头部位置对药物治疗的开角型青光眼(OAG)患者眼压(IOP)的影响。

设计

前瞻性观察研究。

方法

设置:机构研究。

参与者

20例双侧OAG患者,仅接受拉坦前列素治疗。

观察程序

使用ICare Pro眼压计在坐位、仰卧位、右侧和左侧卧位测量眼压。在侧卧位时,以随机顺序在3种不同头部位置(高于胸椎中心30度、低于胸椎中心30度和平行于胸椎中心)测量眼压。

主要观察指标

比较不同头部位置侧卧位时患侧(下方)眼和非患侧眼的眼压。我们还分析了较好眼和较差眼之间眼压的差异。

结果

在侧卧位时,无论头部位置如何,患侧眼的眼压均高于非患侧眼(所有P < 0.05)。与中立或较高头部位置相比,较低的头部位置会增加患侧眼的眼压。然而,较好眼和较差眼在体位或头部位置变化期间眼压升高的幅度没有显著差异。

结论

与侧卧位时的中立头部位置相比,低头部位置会使药物治疗的OAG患者患侧眼的眼压升高。调整枕头高度可能有助于减轻青光眼患者因侧卧时枕头低或无枕头而导致的眼压升高。

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