Hall R C, Kirkpatrick B
Am Fam Physician. 1978 May;17(5):131-4.
The benzodiazepines are remarkably effective anxiolytic drugs. However, they are prone to misuse by both physicians and patients. They should be used in clearly defined clinical situations for short periods, at the lowest possible dosages. Although rare, toxicity can be severe. These agents should be used with caution in persons likely to abuse medication, in the elderly, in patients with glaucoma and in patiens with known hepatic impairment. Sudden cessation may be followed by a withdrawal state.
苯二氮䓬类药物是非常有效的抗焦虑药物。然而，医生和患者都容易滥用它们。它们应在明确界定的临床情况下短期使用，且剂量应尽可能低。虽然罕见，但毒性可能很严重。对于可能滥用药物的人、老年人、青光眼患者以及已知有肝功能损害的患者，应谨慎使用这些药物。突然停药可能会出现戒断状态。
