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原发性肺副神经节瘤:一例报告

Primary paraganglioma of the lung: a case report.

作者信息

Fiorentino Giuseppe, Annunziata Anna, De Rosa Nicolina

机构信息

Division of Respiratory Physiopathology, Monaldi Hospital, Via Leonardo Bianchi, 1, 80131, Naples, Italy.

出版信息

J Med Case Rep. 2015 Sep 2;9:166. doi: 10.1186/s13256-015-0639-z.

DOI:10.1186/s13256-015-0639-z
PMID:26215714
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4557745/
Abstract

INTRODUCTION

Primary paraganglioma of the lung is a rare tumor of which few cases are reported in literature. Both solitary and diffuse primary pulmonary paragangliomas are described. The solitary form of this tumor is rare.

CASE PRESENTATION

We report the case of a 63-year-old Caucasian man with cough, intermittent palpitations and dyspnea. A contrast-enhanced computed tomography scan of his chest revealed a rounded, high-density lesion with irregular profiles measuring 24mm in diameter in the middle lobe. The lesion was suggestive of malignancy. Fine-needle aspiration cytology was performed. The results of the cytological tests were positive for malignant cells. Surgical resection was the choice of treatment. The results of the biochemical tests and postoperative histological examination allowed a definitive diagnosis: primary pulmonary paraganglioma.

CONCLUSIONS

Paragangliomas are identified and characterized with the use of computed tomography and other imaging methods, but for a definitive diagnosis, histopathological evaluation is necessary. We report a rare case of a primary pulmonary paraganglioma that was treated surgically. This case report adds valuable knowledge to the literature on pulmonary paragangliomas.

摘要

引言

肺原发性副神经节瘤是一种罕见肿瘤,文献报道的病例较少。孤立性和弥漫性原发性肺副神经节瘤均有描述。该肿瘤的孤立形式较为罕见。

病例介绍

我们报告一例63岁白种男性患者,有咳嗽、间歇性心悸和呼吸困难症状。其胸部增强计算机断层扫描显示中叶有一个直径24mm的圆形、高密度、轮廓不规则的病变。该病变提示为恶性。进行了细针穿刺细胞学检查。细胞学检查结果显示恶性细胞呈阳性。手术切除是治疗选择。生化检查和术后组织学检查结果得以明确诊断:原发性肺副神经节瘤。

结论

副神经节瘤通过计算机断层扫描和其他成像方法进行识别和特征描述,但要明确诊断,组织病理学评估是必要的。我们报告了一例经手术治疗的罕见原发性肺副神经节瘤病例。本病例报告为肺副神经节瘤的文献增添了有价值的知识。

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