Huang Xiao-Jun, Wu Chengxiang, Chen Xi-Yuan
Department of Respiratory Medicine, Zhejiang Provincial People's Hospital (People's Hospital of Hangzhou Medical College), Hangzhou, China.
Department of Respiratory Medicine, Pujiang County Hospital of Traditional Chinese Medicine of Zhejiang Province, Pujiang, China.
J Int Med Res. 2021 Mar;49(3):3000605211003014. doi: 10.1177/03000605211003014.
A paraganglioma is an extra-adrenal tumor of the paraganglia often found in association with sympathetic and parasympathetic nerves. A primary pulmonary paraganglioma generally presents as multiple small tumors or a solitary mass; however, endobronchial involvement is extremely rare. A 49-year-old man was admitted to our hospital because of a chronic cough, intermittent dyspnea, and chest pain. Chest computed tomography revealed a rounded, high-density lesion in the left lower lung lobe. Fiberoptic bronchoscopy demonstrated an endobronchial mass characterized by smooth, hypervascularized mucosa. Transbronchial biopsy of the mass and immunohistochemistry results suggested a paraganglioma. The patient fully recovered after lobectomy and lymphadenectomy. Pulmonary paragangliomas are rarely reported. Complete surgical resection is considered the treatment of choice for pulmonary paragangliomas, and the long-term prognosis is generally good. However, life-long follow-up is mandatory because of the possibility of recurrence and metastasis. This case report adds valuable knowledge to the literature on pulmonary paragangliomas.
副神经节瘤是一种常与交感神经和副交感神经相关的肾上腺外副神经节肿瘤。原发性肺副神经节瘤通常表现为多个小肿瘤或单个肿块；然而，支气管内受累极为罕见。一名49岁男性因慢性咳嗽、间歇性呼吸困难和胸痛入院。胸部计算机断层扫描显示左下肺叶有一个圆形高密度病变。纤维支气管镜检查发现一个支气管内肿块，其特征为黏膜光滑、血管丰富。对该肿块进行经支气管活检及免疫组化结果提示为副神经节瘤。患者在肺叶切除和淋巴结切除术后完全康复。肺副神经节瘤的报道很少。完整的手术切除被认为是肺副神经节瘤的首选治疗方法，长期预后一般良好。然而，由于有复发和转移的可能性，必须进行终身随访。本病例报告为肺副神经节瘤的文献增添了有价值的知识。
