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对猕猴胼胝体电子显微镜图像中髓鞘g比率的定量分析。

Quantitative analysis of the myelin g-ratio from electron microscopy images of the macaque corpus callosum.

作者信息

Stikov Nikola, Campbell Jennifer S W, Stroh Thomas, Lavelée Mariette, Frey Stephen, Novek Jennifer, Nuara Stephen, Ho Ming-Kai, Bedell Barry J, Dougherty Robert F, Leppert Ilana R, Boudreau Mathieu, Narayanan Sridar, Duval Tanguy, Cohen-Adad Julien, Picard Paul-Alexandre, Gasecka Alicja, Côté Daniel, Pike G Bruce

机构信息

Montreal Neurological Institute, McGill University, Montreal, Canada ; École Polytechnique de Montréal, Montréal, Canada.

Montreal Neurological Institute, McGill University, Montreal, Canada.

出版信息

Data Brief. 2015 Jun 17;4:368-73. doi: 10.1016/j.dib.2015.05.019. eCollection 2015 Sep.

Abstract

We provide a detailed morphometric analysis of eight transmission electron micrographs (TEMs) obtained from the corpus callosum of one cynomolgus macaque. The raw TEM images are included in the article, along with the distributions of the axon caliber and the myelin g-ratio in each image. The distributions are analyzed to determine the relationship between axon caliber and g-ratio, and compared against the aggregate metrics (myelin volume fraction, fiber volume fraction, and the aggregate g-ratio), as defined in the accompanying research article entitled 'In vivo histology of the myelin g-ratio with magnetic resonance imaging' (Stikov et al., NeuroImage, 2015).

摘要

我们对从一只食蟹猕猴的胼胝体获得的八张透射电子显微镜图像(TEM)进行了详细的形态测量分析。文章中包含了原始的TEM图像,以及每张图像中轴突直径和髓鞘g值的分布情况。对这些分布进行分析,以确定轴突直径与g值之间的关系,并与随附的研究文章《磁共振成像下髓鞘g值的体内组织学》(斯蒂科夫等人,《神经影像学》,2015年)中定义的总体指标(髓鞘体积分数、纤维体积分数和总体g值)进行比较。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1eae/4510539/f657e109e2a3/gr1.jpg

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