Kheradvar Arash, Groves Elliott M, Falahatpisheh Ahmad, Mofrad Mohammad K, Hamed Alavi S, Tranquillo Robert, Dasi Lakshmi P, Simmons Craig A, Jane Grande-Allen K, Goergen Craig J, Baaijens Frank, Little Stephen H, Canic Suncica, Griffith Boyce
Department of Biomedical Engineering, The Edwards Lifesciences Center for Advanced Cardiovascular Technology, University of California, Irvine, 2410 Engineering Hall, Irvine, CA, 92697-2730, USA.
Department of Medicine, Division of Cardiology, University of California, Irvine School of Medicine, Irvine, CA, USA.
Ann Biomed Eng. 2015 Oct;43(10):2314-33. doi: 10.1007/s10439-015-1394-4. Epub 2015 Jul 30.
In this final portion of an extensive review of heart valve engineering, we focus on the computational methods and experimental studies related to heart valves. The discussion begins with a thorough review of computational modeling and the governing equations of fluid and structural interaction. We then move onto multiscale and disease specific modeling. Finally, advanced methods related to in vitro testing of the heart valves are reviewed. This section of the review series is intended to illustrate application of computational methods and experimental studies and their interrelation for studying heart valves.
在这篇关于心脏瓣膜工程的广泛综述的最后部分,我们聚焦于与心脏瓣膜相关的计算方法和实验研究。讨论首先全面回顾了计算建模以及流体与结构相互作用的控制方程。接着我们转向多尺度和疾病特异性建模。最后,对与心脏瓣膜体外测试相关的先进方法进行了综述。本综述系列的这一部分旨在阐述计算方法和实验研究在心脏瓣膜研究中的应用及其相互关系。