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黏液性乳腺癌:基于医院病例系列的5年经验回顾性研究

Mucinous Breast Cancer: a Review Study of 5 Year Experience from a Hospital-Based Series of Cases.

作者信息

Dumitru Adrian, Procop Alexandru, Iliesiu Andreea, Tampa Mircea, Mitrache Luminita, Costache Mariana, Sajin Maria, Lazaroiu Anca, Cirstoiu Monica

机构信息

Department of Pathology, Emergency University Hospital, Bucharest, Romania.

Department of Pathology, Emergency University Hospital, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

出版信息

Maedica (Bucur). 2015 Mar;10(1):14-8.

Abstract

BACKGROUND

Mucinous carcinoma (also known as colloid carcinoma) is a particular type of breast cancer characterized by the presence of extracellular mucin and is linked with a more favorable prognosis than invasive breast carcinoma of no special type. Mucinous carcinoma of the breast is an uncommon form of breast tumor, often presenting as a lobulated, moderately well circumscribed mass on mammography, sonography, and MRI imaging. It accounts for 1 to 7% of all breast cancers. Pure mucinous breast carcinomas are rare and account for about 2% of all primary breast carcinomas. Metastatic disease happens at a lower rate than in other types of invasive carcinoma.

METHODS

We present our 5 year experience with this particular pathology in a retrospective review study.

RESULTS

We identified 25 patients with mixed and pure mucinous breast cancer, the tumor size varied greatly from 2 to 19 cm in diameter. A subset of mixed mucinous carcinomas (8 cases) showed neuroendocrine differentiation or other associated premalignant lessions.

CONCLUSION

Mucinous carcinoma of the breast is a rare entity with a favorable prognosis due to low incidence of lymph node metastases. Pure mucinous breast carcinoma has an even rare.

摘要

背景

黏液癌(也称为胶样癌)是一种特殊类型的乳腺癌,其特征是存在细胞外黏液,与非特殊类型的浸润性乳腺癌相比,预后更良好。乳腺黏液癌是一种不常见的乳腺肿瘤形式,在乳腺X线摄影、超声和磁共振成像上常表现为分叶状、边界相对清晰的肿块。它占所有乳腺癌的1%至7%。纯乳腺黏液癌罕见,约占所有原发性乳腺癌的2%。转移疾病的发生率低于其他类型的浸润性癌。

方法

我们在一项回顾性研究中展示了我们对这种特殊病理的5年经验。

结果

我们确定了25例混合性和纯黏液性乳腺癌患者,肿瘤大小差异很大,直径从2厘米到19厘米不等。一部分混合性黏液癌(8例)显示神经内分泌分化或其他相关的癌前病变。

结论

乳腺黏液癌是一种罕见的疾病,由于淋巴结转移发生率低,预后良好。纯乳腺黏液癌更为罕见。

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