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Hatching of Schistosoma mansoni eggs is a Ca2+/calmodulin-dependent process.

作者信息

Katsumata T, Kohno S, Yamaguchi K, Hara K, Aoki Y

机构信息

Second Department of Internal Medicine, Nagasaki University School of Medicine, Japan.

出版信息

Parasitol Res. 1989;76(1):90-1. doi: 10.1007/BF00931079.

DOI:10.1007/BF00931079
PMID:2622901
Abstract

The effect of calcium channel blockers (diltiazem and verapamil) and a calmodulin antagonist (W-7) on the hatching of Schistosoma mansoni eggs in fresh water was studied. The hatching of the eggs was inhibited by diltiazem and W-7 in a dose-dependent fashion and only slightly by verapamil. The present study indicates that the hatching of S. mansoni eggs is a Ca2+/calmodulin-dependent process.

摘要

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2
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Mol Pharmacol. 1982 Sep;22(2):408-12.
3
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