再生医学在器官移植中的应用。
Applications of regenerative medicine in organ transplantation.
作者信息
Jain Aditya, Bansal Ramta
机构信息
Department of Physiology, Government Medical College, Patiala, Punjab, India.
Department of Conservative Dentistry and Endodontics, Institute of Dental Sciences, Sehora, Jammu and Kashmir, India.
出版信息
J Pharm Bioallied Sci. 2015 Jul-Sep;7(3):188-94. doi: 10.4103/0975-7406.160013.
A worldwide shortage of organs for clinical implantation establishes the need to bring forward and test new technologies that will help in solving the problem. The concepts of regenerative medicine hold the potential for augmenting organ function or repairing damaged organ or allowing regeneration of deteriorated organs and tissue. Researchers are exploring possible regenerative medicine applications in organ transplantation so that coming together of the two fields can benefit each other. The present review discusses the strategies that are being implemented to regenerate or bio-engineer human organs for clinical purposes. It also highlights the limitations of the regenerative medicine that needs to be addressed to explore full potential of the field. A web-based research on MEDLINE was done using keywords "regenerative medicine," "tissue-engineering," "bio-engineered organs," "decellularized scaffold" and "three-dimensional printing." This review screened about 170 articles to get the desired knowledge update.
临床移植器官的全球短缺表明有必要提出并测试有助于解决该问题的新技术。再生医学的概念具有增强器官功能、修复受损器官或使退化器官和组织再生的潜力。研究人员正在探索再生医学在器官移植中的可能应用，以便这两个领域的结合能够相互受益。本综述讨论了为临床目的再生或生物工程制造人体器官所采用的策略。它还强调了再生医学的局限性，要充分发掘该领域的潜力就需要解决这些局限性。利用关键词“再生医学”“组织工程”“生物工程器官”“脱细胞支架”和“三维打印”在MEDLINE上进行了基于网络的研究。本综述筛选了约170篇文章以获取所需的知识更新。
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