Dutra Roos Bruno, Valdomiro Roos Milton, Camisa Júnior Antero, Moreno Ungaretti Lima Ezequiel, Noshang Pereira Rafael, Luciano Zangirolami Maurício, Machado de Albuquerque Gisela
Hospital Ortopédico de Passo Fundo (HOPF), Passo Fundo, RS, Brazil.
Hospital São Vicente de Paulo de Passo Fundo (HSVP), Passo Fundo, RS, Brazil.
Rev Bras Ortop. 2014 Mar 20;49(4):386-90. doi: 10.1016/j.rboe.2014.03.005. eCollection 2014 Jul-Aug.
To conduct an epidemiological analysis on the main microbiological markers in bone tissue that was processed at the musculoskeletal tissue bank of Hospital São Vicente de Paulo, in Passo Fundo, between August 2007 and October 2011.
Between August 2007 and October 2011, 202 musculoskeletal tissue samples were collected for the tissue bank. Among these, 159 samples were from living donor patients and 43 were from cadaver donors. The following serological tests were requested: hepatitis B, hepatitis C, syphilis, cytomegalovirus, Chagas disease, toxoplasmosis, HIV and HTLV.
Among the 159 living donors, 103 (64.75%) were men and 56 (35.25%) were women. The patients' mean age was 59.35 ± 8.87 years. Out of this total, 76 tissue samples (47.8%) from donors were rejected. There was no difference in the number of rejections in relation to sex (p = 0.135) or age (p = 0.523). The main cause of rejection was serologically positive findings for the hepatitis B virus, which was responsible for 48 rejections (63.15%). Among the 43 cadaver donors, the mean age was 37.84 ± 10.32 years. Of these, 27 (62.8%) were men and 16 (37.2%) were women. Six of the samples collected from cadaver donors were rejected (13.9%), and the main cause of rejection was serologically positive findings for the hepatitis C virus, which was responsible for three cases (50%). There was no significant difference in the number of rejections in relation to sex (p = 0.21) or age (p = 0.252).
There were a greater number of rejections of tissues from living donors (47.8%) than from cadaver donors (13.9%). Among the living donors, the main cause of rejection was the presence of serologically positive findings of the hepatitis B virus, while among the cadaver donors, it was due to the hepatitis C virus.
对2007年8月至2011年10月间在帕索丰杜圣保罗医院肌肉骨骼组织库处理的骨组织中的主要微生物标志物进行流行病学分析。
2007年8月至2011年10月间，为该组织库收集了202份肌肉骨骼组织样本。其中，159份样本来自活体供体患者，43份来自尸体供体。要求进行以下血清学检测：乙肝、丙肝、梅毒、巨细胞病毒、恰加斯病、弓形虫病、艾滋病毒和人类嗜T淋巴细胞病毒。
在159名活体供体中，103名（64.75%）为男性，56名（35.25%）为女性。患者的平均年龄为59.35±8.87岁。其中，来自供体的76份组织样本（47.8%）被拒收。拒收数量在性别（p = 0.135）或年龄（p = 0.523）方面没有差异。拒收的主要原因是乙肝病毒血清学检测呈阳性，导致48例拒收（63.15%）。在43名尸体供体中，平均年龄为37.84±10.32岁。其中，27名（62.8%）为男性，16名（37.2%）为女性。从尸体供体收集的样本中有6份被拒收（13.9%），拒收的主要原因是丙肝病毒血清学检测呈阳性，导致3例（50%）。拒收数量在性别（p = 0.21）或年龄（p = 0.252）方面没有显著差异。
活体供体组织的拒收数量（47.8%）多于尸体供体组织（13.9%）。在活体供体中，拒收的主要原因是乙肝病毒血清学检测呈阳性，而在尸体供体中，原因是丙肝病毒。
