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Commentary: Toward a new focus in antibiotic and drug discovery from the Streptomyces arsenal.

作者信息

Dhakal Dipesh, Sohng Jae Kyung

机构信息

Institute of Biomolecule Reconstruction (iBR), Department of BT-Convergent Pharmaceutical Engineering, Sun Moon University Asan, South Korea.

出版信息

Front Microbiol. 2015 Jul 16;6:727. doi: 10.3389/fmicb.2015.00727. eCollection 2015.

DOI:10.3389/fmicb.2015.00727
PMID:26236304
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4503920/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd9/4503920/17c6d60543d8/fmicb-06-00727-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd9/4503920/17c6d60543d8/fmicb-06-00727-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd9/4503920/17c6d60543d8/fmicb-06-00727-g0001.jpg

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本文引用的文献

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Front Microbiol. 2015 May 13;6:461. doi: 10.3389/fmicb.2015.00461. eCollection 2015.
2
Recent advances in combinatorial biosynthesis for drug discovery.药物发现中组合生物合成的最新进展。
Drug Des Devel Ther. 2015 Feb 12;9:823-33. doi: 10.2147/DDDT.S63023. eCollection 2015.
3
Mechanisms of antibiotic resistance.抗生素耐药机制。
J Ind Microbiol Biotechnol. 2019 Mar;46(3-4):385-407. doi: 10.1007/s10295-018-02120-y. Epub 2019 Jan 18.
4
Improved production of 1-deoxynojirymicin in Escherichia coli through metabolic engineering.通过代谢工程提高大肠杆菌中 1-去氧野尻霉素的产量。
World J Microbiol Biotechnol. 2018 May 23;34(6):77. doi: 10.1007/s11274-018-2462-3.
5
Marine Rare Actinobacteria: Isolation, Characterization, and Strategies for Harnessing Bioactive Compounds.海洋稀有放线菌：生物活性化合物的分离、表征及利用策略
Front Microbiol. 2017 Jun 15;8:1106. doi: 10.3389/fmicb.2017.01106. eCollection 2017.
6
Coalition of Biology and Chemistry for Ameliorating Antimicrobial Drug Discovery.生物与化学促进抗菌药物研发联盟
Front Microbiol. 2017 May 4;8:734. doi: 10.3389/fmicb.2017.00734. eCollection 2017.
7
Microbial production of astilbin, a bioactive rhamnosylated flavanonol, from taxifolin.从紫杉叶素微生物生产具有生物活性的鼠李糖基化黄烷醇二氢槲皮素。
World J Microbiol Biotechnol. 2017 Feb;33(2):36. doi: 10.1007/s11274-017-2208-7. Epub 2017 Jan 24.
8
StreptomeDB 2.0--an extended resource of natural products produced by streptomycetes.链霉菌数据库2.0——链霉菌产生的天然产物的扩展资源。
Nucleic Acids Res. 2016 Jan 4;44(D1):D509-14. doi: 10.1093/nar/gkv1319. Epub 2015 Nov 28.
Front Microbiol. 2015 Feb 5;6:34. doi: 10.3389/fmicb.2015.00034. eCollection 2015.
4
Enhanced production of nargenicin A(1) and generation of novel glycosylated derivatives.纳杰尼菌素A(1)产量提高及新型糖基化衍生物的产生。
Appl Biochem Biotechnol. 2015 Mar;175(6):2934-49. doi: 10.1007/s12010-014-1472-3. Epub 2015 Jan 11.
5
Metabolic engineering of antibiotic factories: new tools for antibiotic production in actinomycetes.抗生素工厂的代谢工程：放线菌中抗生素生产的新工具。
Trends Biotechnol. 2015 Jan;33(1):15-26. doi: 10.1016/j.tibtech.2014.10.009. Epub 2014 Dec 10.
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Formulation and Statistical Optimization of Culture Medium for Improved Production of Antimicrobial Compound by Streptomyces sp. JAJ06.用于提高链霉菌JAJ06抗菌化合物产量的培养基配方及统计优化
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Synthetic biology of secondary metabolite biosynthesis in actinomycetes: Engineering precursor supply as a way to optimize antibiotic production.放线菌次生代谢物生物合成的合成生物学：工程前体供应作为优化抗生素生产的一种方法。
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