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颅内指突状树突细胞肉瘤:首例病例报告。

Intracranial Interdigitating Dendritic Cell Sarcoma: First Case Report.

作者信息

Hutter Gregor, Hofer Silvia, Tzankov Alexandar, Kothbauer Karl F

机构信息

Divisions of *Neurosurgery and ‡Oncology, Luzerner Kantonsspital, Luzern, Switzerland; §Pathology Department, Universitätsspital Basel, Basel, Switzerland; ¶Division of Neurosurgery, University of Basel, Basel, Switzerland.

出版信息

Neurosurgery. 2015 Dec;77(6):E979-83. doi: 10.1227/NEU.0000000000000925.

DOI:10.1227/NEU.0000000000000925
PMID:26237342
Abstract

BACKGROUND AND IMPORTANCE

This is the first report of a primarily intracranial interdigitating dendritic cell sarcoma (IDCS).

CLINICAL PRESENTATION

A 39-year-old patient with right hemiparesis underwent complete resection of a large parafalcine tumor with subsequent complete recovery of neurological symptoms. Histologically, the tumor was diagnosed as IDCS. Extensive staging did not reveal any extracranial manifestation of this disease. After 1.5 years, the patient remains recurrence free and is being observed closely.

CONCLUSION

IDCS are exceedingly rare tumors and so far have not been found intracranially. On the basis of the limited experience with extracranial occurrence, this tumor is best managed by complete resection and careful oncological observation.

ABBREVIATIONS

FDCS, follicular dendritic cell sarcomaIDCS, interdigitating dendritic cell sarcomaRTU, ready-to-use kit.

摘要

背景与重要性

这是首例原发性颅内指突状树突细胞肉瘤(IDCS)的报告。

临床表现

一名39岁右侧偏瘫患者接受了巨大镰旁肿瘤的全切手术,术后神经症状完全恢复。组织学检查显示,该肿瘤被诊断为IDCS。全面分期检查未发现该疾病的任何颅外表现。1.5年后,患者无复发,仍在密切观察中。

结论

IDCS极为罕见,迄今为止尚未在颅内发现。基于颅外发病的有限经验,该肿瘤最佳的治疗方法是全切并进行仔细的肿瘤学观察。

缩写

FDCS,滤泡树突细胞肉瘤;IDCS,指突状树突细胞肉瘤;RTU,即用试剂盒

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