双胞胎的筛查与侵入性检测
Screening and Invasive Testing in Twins.
作者信息
Monni Giovanni, Iuculano Ambra, Zoppi Maria Angelica
机构信息
Department of Obstetrics and Gynecology, Prenatal and Preimplantation Genetic Diagnosis, Fetal Therapy, Ospedale Microcitemico, via Jenner, 09121 Cagliari, Italy.
出版信息
J Clin Med. 2014 Jul 29;3(3):865-82. doi: 10.3390/jcm3030865.
Abstract
Prenatal screening and testing for trisomy 21 in twin pregnancies poses a number of challenges: the exact estimate of the a priori risk of trisomy 21, the choice of prenatal screening test and/or invasive techniques to employ for the diagnosis and the impact of the result on the options of treatment in case of discordant results within a twin pair or among multiples. These different aspects are discussed below while recognizing that many issues remain unresolved.
摘要
双胎妊娠中21三体综合征的产前筛查和检测存在诸多挑战：21三体综合征先验风险的准确估计、用于诊断的产前筛查试验和/或侵入性技术的选择，以及在双胎或多胎中结果不一致时结果对治疗选择的影响。以下将讨论这些不同方面，同时认识到许多问题仍未得到解决。
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