Cerdá Magdalena, Tracy Melissa, Keyes Katherine M, Galea Sandro
From the aViolence Prevention Research Program, University of California, Davis, Sacramento, CA; bDepartment of Emergency Medicine, School of Medicine, University of California, Davis, Sacramento, CA; cDepartment of Epidemiology, University at Albany School of Public Health, Rensselaer, NY; dDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, NY; and eSchool of Public Health, Boston University, Boston, MA.
Epidemiology. 2015 Sep;26(5):681-9. doi: 10.1097/EDE.0000000000000350.
Violence-related post-traumatic stress disorder (PTSD) remains a prevalent and disabling psychiatric disorder in urban areas. However, the most effective allocation of resources into prevention and treatment to reduce this problem is unknown. We contrasted the impact of two interventions on violence-related PTSD: (1) a population-level intervention intended to prevent violence (i.e., hot-spot policing), and (2) an individual-level intervention intended to shorten PTSD duration (i.e., cognitive-behavioral therapy-CBT).
We used agent-based modeling to simulate violence and PTSD in New York City under four scenarios: (1) no intervention, (2) targeted policing to hot spots of violence, (3) increased access to CBT for people who suffered from violence-related PTSD, and (4) a combination of the two interventions.
Combined prevention and treatment produced the largest decrease in violence-related PTSD prevalence: hot-spot policing plus a 50% increase in CBT for 5 years reduced the annual prevalence of violence-related PTSD from 3.6% (95% confidence interval = 3.5%, 3.6%) to 3.4% (3.3%, 3.5%). It would have been necessary to implement hot-spot policing or to increase CBT by 200% for 10 years for either intervention to achieve the same reduction in isolation.
This study provides an empirically informed demonstration that investment in combined strategies that target social determinants of mental illness and provide evidence-based treatment to those affected by psychiatric disorders can produce larger reductions in the population burden from violence-related PTSD than either preventive or treatment interventions alone. However, neither hot-spot policing nor CBT, alone or combined, will produce large shifts in the population prevalence of violence-related PTSD.
与暴力相关的创伤后应激障碍(PTSD)在城市地区仍然是一种普遍且致残的精神障碍。然而,尚不清楚将资源最有效地分配到预防和治疗中以减少这一问题的方法。我们对比了两种干预措施对与暴力相关的PTSD的影响:(1)旨在预防暴力的人群层面干预措施(即热点地区治安管理),以及(2)旨在缩短PTSD病程的个体层面干预措施(即认知行为疗法 - CBT)。
我们使用基于主体的模型在四种情景下模拟纽约市的暴力和PTSD情况:(1)无干预,(2)针对暴力热点地区的治安管理,(3)增加对遭受与暴力相关PTSD者的CBT治疗机会,以及(4)两种干预措施的组合。
预防与治疗相结合使与暴力相关的PTSD患病率下降幅度最大:热点地区治安管理加上5年内CBT治疗机会增加50%,使与暴力相关的PTSD年患病率从3.6%(95%置信区间 = 3.5%,3.6%)降至3.4%(3.3%,3.5%)。若单独实施热点地区治安管理或CBT治疗机会增加200%并持续10年,才能实现相同程度的患病率降低。
本研究提供了一项基于实证的论证,即投资于针对精神疾病社会决定因素的联合策略,并为受精神障碍影响者提供循证治疗,相较于单独的预防或治疗干预措施,能够更大程度地减轻与暴力相关的PTSD给人群带来的负担。然而,无论是单独的热点地区治安管理还是CBT,亦或是两者结合,都不会使与暴力相关的PTSD人群患病率发生大幅变化。