一种优化的半自动速率法测定血清谷胱甘肽还原酶活性及其在恶性疾病患者中的应用
An optimized semi-automatic rate method for serum glutathione reductase activity and its application to patients with malignant disease.
作者信息
Delides A, Spooner R J, Goldberg D M, Neal F E
出版信息
J Clin Pathol. 1976 Jan;29(1):73-7. doi: 10.1136/jcp.29.1.73.
Abstract
An improved and optimized method for serum glutathione reductase is described. The reference range for normal subjects is 47-79 IU/1. The method is more sensitive than conventional enzyme tests in the detection of malignant disease. It was not raised more frequently in patients with clinical evidence of metastases than in those clinically free of such metastases, and it did not seem to correlate with prognosis among those patients who failed to survive six months from the time the analysis was first conducted.
摘要
本文描述了一种改进和优化的血清谷胱甘肽还原酶检测方法。正常受试者的参考范围为47 - 79 IU/1。该方法在检测恶性疾病方面比传统酶检测更敏感。有转移临床证据的患者中，该指标升高的频率并不比无此类转移的患者更高，而且在首次进行分析后未能存活六个月的患者中，该指标似乎与预后无关。
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An optimized semi-automatic rate method for serum glutathione reductase activity and its application to patients with malignant disease.一种优化的半自动速率法测定血清谷胱甘肽还原酶活性及其在恶性疾病患者中的应用
J Clin Pathol. 1976 Jan;29(1):73-7. doi: 10.1136/jcp.29.1.73.
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[Erythrocyte glutathione reductase (EGR)].
Nihon Rinsho. 2004 Dec;62 Suppl 12:809-11.
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Method for the detection of a biochemical riboflavin deficiency. Stimulation of NADPH2-dependent glutathione reductase from human erythrocytes by FAD in vitro. Investigations on the vitamin B2 status in healthly people and geriatric patients.检测生化性核黄素缺乏的方法。体外FAD对人红细胞中NADPH2依赖性谷胱甘肽还原酶的刺激作用。对健康人群和老年患者维生素B2状态的研究。
Int Z Vitaminforsch. 1970;40(2):166-83.
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[Determination of glutathione reductase activity in erythrocytes and whole blood as an indicator of riboflavin nutrition].[测定红细胞和全血中谷胱甘肽还原酶活性作为核黄素营养指标]
Acta Vitaminol Enzymol. 1983;5(3):171-8.
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Effect of riboflavin depletion and repletion on the erythrocyte glutathione reductase in the rat.核黄素缺乏与补充对大鼠红细胞谷胱甘肽还原酶的影响。
J Nutr. 1971 Nov;101(11):1459-66. doi: 10.1093/jn/101.11.1459.
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Erythrocyte glutathione reductase--a measure of riboflavin nutritional status.红细胞谷胱甘肽还原酶——核黄素营养状况的一种衡量指标。
Nutr Rev. 1972 Jul;30(7):162-4. doi: 10.1111/j.1753-4887.1972.tb04027.x.
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