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NNMT: A Bad Actor in Fat Makes Good in Liver.
Cell Metab. 2015 Aug 4;22(2):200-1. doi: 10.1016/j.cmet.2015.07.017.
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Body weight predicts Nicotinamide N-Methyltransferase activity in mouse fat.
Endocr Res. 2018 Feb;43(1):55-63. doi: 10.1080/07435800.2017.1381972. Epub 2017 Oct 16.
4
Inhibiting proliferation in KB cancer cells by RNA interference-mediated knockdown of nicotinamide N-methyltransferase expression.
Int J Immunopathol Pharmacol. 2011 Jan-Mar;24(1):69-77. doi: 10.1177/039463201102400109.
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Nicotinamide N-methyltransferase increases complex I activity in SH-SY5Y cells via sirtuin 3.
Biochem Biophys Res Commun. 2015 Nov 20;467(3):491-6. doi: 10.1016/j.bbrc.2015.10.023. Epub 2015 Oct 8.
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Nicotinamide N-Methyltransferase: More Than a Vitamin B3 Clearance Enzyme.
Trends Endocrinol Metab. 2017 May;28(5):340-353. doi: 10.1016/j.tem.2017.02.004. Epub 2017 Mar 11.
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HPLC-UV method for measuring nicotinamide N-methyltransferase activity in biological samples: evidence for substrate inhibition kinetics.
J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Mar 15;921-922:87-95. doi: 10.1016/j.jchromb.2013.01.030. Epub 2013 Feb 4.

引用本文的文献

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Nicotinamide N-methyltransferase inhibition mitigates obesity-related metabolic dysfunction.
Diabetes Obes Metab. 2024 Nov;26(11):5272-5282. doi: 10.1111/dom.15879. Epub 2024 Aug 19.
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Nicotinamide N-methyltransferase (NNMT): a novel therapeutic target for metabolic syndrome.
Front Pharmacol. 2024 Jun 11;15:1410479. doi: 10.3389/fphar.2024.1410479. eCollection 2024.
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Molecular Mechanisms of IL18 in Disease.
Int J Mol Sci. 2023 Dec 6;24(24):17170. doi: 10.3390/ijms242417170.
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Nicotinamide N-methyltransferase and liver diseases.
Genes Dis. 2022 Apr 20;10(5):1883-1893. doi: 10.1016/j.gendis.2022.03.019. eCollection 2023 Sep.
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Nicotinamide -Methyltransferase in Health and Cancer.
Int J Tryptophan Res. 2017 Jun 30;10:1178646917691739. doi: 10.1177/1178646917691739. eCollection 2017.
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Roles of Nicotinamide N-Methyltransferase in Obesity and Type 2 Diabetes.
Biomed Res Int. 2021 Jul 27;2021:9924314. doi: 10.1155/2021/9924314. eCollection 2021.

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Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.
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Targeted, LCMS-based Metabolomics for Quantitative Measurement of NAD(+) Metabolites.
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SIRT1 and other sirtuins in metabolism.
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Mitochondrial protein acetylation as a cell-intrinsic, evolutionary driver of fat storage: chemical and metabolic logic of acetyl-lysine modifications.
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NAD+ metabolism in health and disease.
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