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1
Nicotinamide N-Methyltransferase: More Than a Vitamin B3 Clearance Enzyme.
Trends Endocrinol Metab. 2017 May;28(5):340-353. doi: 10.1016/j.tem.2017.02.004. Epub 2017 Mar 11.
2
Nicotinamide N-methyltransferase: At the crossroads between cellular metabolism and epigenetic regulation.
Mol Metab. 2021 Mar;45:101165. doi: 10.1016/j.molmet.2021.101165. Epub 2021 Jan 14.
3
Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.
Nature. 2014 Apr 10;508(7495):258-62. doi: 10.1038/nature13198.
4
Citrullination Inactivates Nicotinamide- N-methyltransferase.
ACS Chem Biol. 2018 Sep 21;13(9):2663-2672. doi: 10.1021/acschembio.8b00578. Epub 2018 Aug 8.
5
Kinetic Mechanism of Nicotinamide N-Methyltransferase.
Biochemistry. 2018 Sep 25;57(38):5524-5532. doi: 10.1021/acs.biochem.8b00775. Epub 2018 Sep 10.
7
Complex roles of nicotinamide N-methyltransferase in cancer progression.
Cell Death Dis. 2022 Mar 25;13(3):267. doi: 10.1038/s41419-022-04713-z.
9
A Rapid and Efficient Assay for the Characterization of Substrates and Inhibitors of Nicotinamide N-Methyltransferase.
Biochemistry. 2016 Sep 20;55(37):5307-15. doi: 10.1021/acs.biochem.6b00733. Epub 2016 Sep 9.
10
Novel Inhibitors of Nicotinamide--Methyltransferase for the Treatment of Metabolic Disorders.
Molecules. 2021 Feb 13;26(4):991. doi: 10.3390/molecules26040991.

引用本文的文献

1
Inflammatory Crosstalk Between Type 2 Diabetes and Sarcopenia: Insights from In Silico Evaluation.
Int J Mol Sci. 2025 Aug 17;26(16):7932. doi: 10.3390/ijms26167932.
4
NNMT/1-MNA protects against hepatic ischemia-reperfusion injury through the AKT/FOXO1/ANGPT2/JNK axis.
Nat Commun. 2025 May 22;16(1):4779. doi: 10.1038/s41467-025-59968-9.
6
Nicotinamide N-Methyltransferase in the Inflammatory Pathogenesis of Graves' Orbitopathy.
Invest Ophthalmol Vis Sci. 2025 May 1;66(5):3. doi: 10.1167/iovs.66.5.3.
7
Nicotinamide metabolism reprogramming drives reversible senescence of glioblastoma cells.
Cell Mol Life Sci. 2025 Mar 21;82(1):126. doi: 10.1007/s00018-025-05641-9.
8
Increasing cellular NAD protects hepatocytes against palmitate-induced lipotoxicity by preventing PARP-1 inhibition and the mTORC1-p300 pathway activation.
Am J Physiol Cell Physiol. 2025 Mar 1;328(3):C776-C790. doi: 10.1152/ajpcell.00946.2024. Epub 2025 Jan 27.
9
Mechanisms and rationales of SAM homeostasis.
Trends Biochem Sci. 2025 Mar;50(3):242-254. doi: 10.1016/j.tibs.2024.12.009. Epub 2025 Jan 15.

本文引用的文献

1
NNMT Silencing Activates Tumor Suppressor PP2A, Inactivates Oncogenic STKs, and Inhibits Tumor Forming Ability.
Clin Cancer Res. 2017 May 1;23(9):2325-2334. doi: 10.1158/1078-0432.CCR-16-1323. Epub 2016 Nov 3.
3
Nicotinamide riboside is uniquely and orally bioavailable in mice and humans.
Nat Commun. 2016 Oct 10;7:12948. doi: 10.1038/ncomms12948.
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NAD(+) metabolism: Bioenergetics, signaling and manipulation for therapy.
Biochim Biophys Acta. 2016 Dec;1864(12):1787-1800. doi: 10.1016/j.bbapap.2016.06.014. Epub 2016 Jun 29.
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Nicotinamide Riboside Opposes Type 2 Diabetes and Neuropathy in Mice.
Sci Rep. 2016 May 27;6:26933. doi: 10.1038/srep26933.
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NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice.
Science. 2016 Jun 17;352(6292):1436-43. doi: 10.1126/science.aaf2693. Epub 2016 Apr 28.
9
The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition.
Nat Cell Biol. 2015 Dec;17(12):1523-35. doi: 10.1038/ncb3264. Epub 2015 Nov 16.
10
1-Methylnicotinamide ameliorates lipotoxicity-induced oxidative stress and cell death in kidney proximal tubular cells.
Free Radic Biol Med. 2015 Dec;89:831-41. doi: 10.1016/j.freeradbiomed.2015.10.414. Epub 2015 Oct 19.

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