Ducassou Stéphane, Rivaud Delphine, Auvrignon Anne, Vérité Cécile, Bertrand Yves, Gandemer Virginie, Leverger Guy
From the *Unité d'Oncologie Hématologie Pédiatrique, Hôpital des Enfants, Groupe Hospitalier, Pellegrin, CHU de Bordeaux, Bordeaux Cedex, France; †Service d'Onco-Hématologie Pédiatrique, Hôpital Armand-Trousseau, Paris Cedex, France; ‡Institut d'Hématologie Oncologie Pédiatrique, CHU Lyon, Lyon Cedex, France; and §Unité d'Hémato-Oncologie Pédiatrique, CHU Hôpital Sud, Rennes Cedex, France.
Pediatr Infect Dis J. 2015 Nov;34(11):1262-4. doi: 10.1097/INF.0000000000000875.
This study investigates invasive fungal infections (IFIs) in patients with acute myelogenous leukemia who were included in the Enfant Leucemie Aigue 02 protocol between 2005 and 2011. Among 387 patients, 15 had aspergillosis, 9 had candidiasis, and 2 had mucormycosis. The most frequent localization of IFIs was in the lungs. It was found that after a median of 34 months, 2 deaths were attributable to IFI without any difference in survival between the groups with and without IFI.
本研究调查了2005年至2011年间纳入儿童急性白血病02方案的急性髓性白血病患者的侵袭性真菌感染（IFI）情况。在387例患者中，15例患有曲霉病，9例患有念珠菌病，2例患有毛霉病。IFI最常见的感染部位是肺部。研究发现，在中位时间34个月后，有2例死亡归因于IFI，IFI组和非IFI组之间的生存率无差异。
