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使用微型多平面经食管超声心动图探头对伴有心肺衰竭的 ICU 通气患者进行血流动力学评估。

Hemodynamic assessment of ventilated ICU patients with cardiorespiratory failure using a miniaturized multiplane transesophageal echocardiography probe.

机构信息

Medical-Surgical ICU, Réanimation Polyvalente, CHU Dupuytren, Dupuytren University Hospital, 2 avenue Martin Luther King, 87042, Limoges, France.

Faculty of Medicine, University of Limoges, Limoges, France.

出版信息

Intensive Care Med. 2015 Nov;41(11):1886-94. doi: 10.1007/s00134-015-3998-4. Epub 2015 Aug 8.

Abstract

PURPOSE

To assess the feasibility, image quality, diagnostic accuracy, therapeutic impact and tolerance of diagnostic and hemodynamic assessment using a novel miniaturized multiplane transesophageal echocardiography (TEE) probe in ventilated ICU patients with cardiopulmonary compromise.

STUDY DESIGN

Prospective, descriptive, single-center study.

METHODS

Fifty-seven ventilated patients with acute circulatory or respiratory failure were assessed, using a miniaturized multiplane TEE probe and a standard TEE probe used as reference, randomly by two independent experienced operators. Measurements of hemodynamic parameters were independently performed off-line by a third expert. Diagnostic groups of acute circulatory failure (n = 5) and of acute respiratory failure (n = 3) were distinguished. Hemodynamic monitoring was performed in 9 patients using the miniaturized TEE probe. TEE tolerance and therapeutic impact were reported.

RESULTS

The miniaturized TEE probe was easier to insert than the standard TEE probe. Despite lower imaging quality of the miniaturized TEE probe, the two probes had excellent diagnostic agreement in patients with acute circulatory failure (Kappa: 0.95; 95% CI: 0.85-1) and with acute respiratory failure (Kappa: 1; 95% CI: 1.0-1.0). Accordingly, therapeutic strategies derived from both TEE examinations were concordant (Kappa: 0.82; 95% CI: 0.66-0.97). The concordance between quantitative hemodynamic parameters obtained with both TEE probes was also excellent. No relevant complication secondary to TEE probes insertion occurred.

CONCLUSIONS

Hemodynamic assessment of ventilated ICU patients with cardiopulmonary compromise using a miniaturized multiplane TEE probe appears feasible, well-tolerated, and relevant in terms of diagnostic information and potential therapeutic impact. Further larger-scale studies are needed to confirm these preliminary results.

摘要

目的

评估在心肺功能受损的通气 ICU 患者中使用新型微型多平面经食管超声心动图(TEE)探头进行诊断和血液动力学评估的可行性、图像质量、诊断准确性、治疗效果和耐受性。

研究设计

前瞻性、描述性、单中心研究。

方法

使用微型多平面 TEE 探头和标准 TEE 探头(作为参考)对 57 例急性循环或呼吸衰竭的通气患者进行评估,由两位独立的经验丰富的操作人员进行随机检查。由第三位专家进行独立的离线血液动力学参数测量。将急性循环衰竭(n=5)和急性呼吸衰竭(n=3)的诊断组进行区分。在 9 例患者中使用微型 TEE 探头进行血液动力学监测。报告 TEE 耐受性和治疗效果。

结果

微型 TEE 探头比标准 TEE 探头更容易插入。尽管微型 TEE 探头的成像质量较低,但在急性循环衰竭患者(Kappa:0.95;95%置信区间:0.85-1)和急性呼吸衰竭患者(Kappa:1;95%置信区间:1.0-1.0)中,两种探头具有出色的诊断一致性。因此,来自两种 TEE 检查的治疗策略是一致的(Kappa:0.82;95%置信区间:0.66-0.97)。两种 TEE 探头获得的定量血液动力学参数之间的一致性也非常好。未发生与 TEE 探头插入相关的任何相关并发症。

结论

使用微型多平面 TEE 探头对心肺功能受损的通气 ICU 患者进行血液动力学评估似乎是可行的,患者耐受性良好,在诊断信息和潜在治疗效果方面具有重要意义。需要进一步进行更大规模的研究来证实这些初步结果。

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