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慢性钙化性胰腺炎合并隐匿性脾破裂一例并文献复习

Occult splenic rupture in a case of chronic calcific pancreatitis with a brief review of literature.

作者信息

S Sharada, Olakkengil S, Rozario A P

机构信息

Department of General Surgery, St John's Medical College Hospital, Bangalore, India.

Department of General Surgery, St John's Medical College Hospital, Bangalore, India.

出版信息

Int J Surg Case Rep. 2015;14:95-7. doi: 10.1016/j.ijscr.2015.06.015. Epub 2015 Jun 20.

Abstract

INTRODUCTION

Splenic rupture in chronic pancreatitis is a life threatening rare complication. The anatomical proximity of the pancreas with the spleen and the pathophysiological process in acute and chronic pancreatitis form the basis of this dreaded complication.

PRESENTATION OF CASE

We cite the case of a young male previously undiagnosed with chronic pancreatitis presenting with atraumatic splenic rupture. Definitive diagnosis was made by contrast enhanced computed tomography of the abdomen, intra operative findings, and histopathological examination of the splenectomy specimen.

DISCUSSION

The splenorenal ligament forms the main anatomic proximity between the pancreas and the spleen. A few pathophysiological mechanisms though suggested are incompletely understood. splenic vein thrombosis, intrasplenic pseudocysts, splenic rupture, infarction, necrosis, splenic hematoma, and severe bleeding from eroded splenic vessels are the complications noted of which splenic rupture is the second most common following splenic vein thrombosis forming 36% of the complications noted. Chronic pancreatitis as an etiology of occult splenic rupture is rare and forms 8.27% of cases; commonest causes being neoplastic and infectious. The diagnosis is based on clinical and radiological findings and the management is predominantly surgical.

CONCLUSION

High clinical suspicion on the part of the treating physician and the emergency team is essential to the management of atraumatic splenic rupture. The increasing understanding of the pathophysiology and presentation of splenic complications in pancreatitis may alert the index physician to these fatal complications.

摘要

引言

慢性胰腺炎并发脾破裂是一种危及生命的罕见并发症。胰腺与脾脏在解剖位置上相邻,以及急慢性胰腺炎的病理生理过程构成了这一可怕并发症的基础。

病例介绍

我们列举一例此前未被诊断出患有慢性胰腺炎的年轻男性,他出现了非创伤性脾破裂。通过腹部增强计算机断层扫描、术中发现以及脾切除标本的组织病理学检查做出了明确诊断。

讨论

脾肾韧带构成了胰腺与脾脏之间主要的解剖相邻关系。虽然提出了一些病理生理机制,但尚未完全理解。脾静脉血栓形成、脾内假性囊肿、脾破裂、梗死、坏死、脾血肿以及脾血管侵蚀导致的严重出血是所观察到的并发症,其中脾破裂是继脾静脉血栓形成之后第二常见的并发症,占所观察到并发症的36%。慢性胰腺炎作为隐匿性脾破裂的病因较为罕见,占病例的8.27%;最常见的病因是肿瘤性和感染性。诊断基于临床和影像学检查结果,治疗主要是手术治疗。

结论

治疗医生和急诊团队高度的临床怀疑对于非创伤性脾破裂的治疗至关重要。对胰腺炎中脾并发症病理生理过程和表现的日益了解可能会提醒首诊医生注意这些致命并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4edd/4573206/bfa3f8180cfe/gr1.jpg

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