单峰骆驼与中东呼吸综合征冠状病毒（MERS-CoV）的传播
Dromedary Camels and the Transmission of Middle East Respiratory Syndrome Coronavirus (MERS-CoV).
作者信息
Hemida M G, Elmoslemany A, Al-Hizab F, Alnaeem A, Almathen F, Faye B, Chu D K W, Perera R A P M, Peiris M
机构信息
Department of Microbiology and Parasitology, College of Veterinary Medicine and Animal Resources, King Faisal University, Al-Hsa, Saudi Arabia.
Department of Virology, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh, Egypt.
出版信息
Transbound Emerg Dis. 2017 Apr;64(2):344-353. doi: 10.1111/tbed.12401. Epub 2015 Aug 10.
Middle East respiratory syndrome coronavirus (MERS-CoV) is an existential threat to global public health. The virus has been repeatedly detected in dromedary camels (Camelus dromedarius). Adult animals in many countries in the Middle East as well as in North and East Africa showed high (>90%) seroprevalence to the virus. Middle East respiratory syndrome coronavirus isolated from dromedaries is genetically and phenotypically similar to viruses from humans. We summarize current understanding of the ecology of MERS-CoV in animals and transmission at the animal-human interface. We review aspects of husbandry, animal movements and trade and the use and consumption of camel dairy and meat products in the Middle East that may be relevant to the epidemiology of MERS. We also highlight the gaps in understanding the transmission of this virus in animals and from animals to humans.
中东呼吸综合征冠状病毒（MERS-CoV）对全球公共卫生构成了生存威胁。该病毒已在单峰骆驼（骆驼属单峰驼）中多次被检测到。中东以及北非和东非许多国家的成年动物对该病毒表现出高血清阳性率（>90%）。从单峰骆驼中分离出的中东呼吸综合征冠状病毒在基因和表型上与人类病毒相似。我们总结了目前对MERS-CoV在动物中的生态学以及在动物与人类界面传播的理解。我们回顾了中东地区畜牧业、动物移动和贸易以及骆驼乳制品和肉制品的使用和消费等可能与MERS流行病学相关的方面。我们还强调了在理解该病毒在动物中的传播以及从动物到人类传播方面的差距。
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