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髋部骨折后1年死亡率的预测因素:对465例连续患者的回顾性研究

Predictors for 1-year mortality following hip fracture: a retrospective review of 465 consecutive patients.

作者信息

Heyes G J, Tucker A, Marley D, Foster A

机构信息

, Apartment 1001, 70 Chichester Street, Belfast, BT1 4JQ, UK.

Department of Trauma and Orthopaedics, Altnagelvin Hospital, Glenshane Road, County Londonderry, BT47 6SB, Northern Ireland.

出版信息

Eur J Trauma Emerg Surg. 2017 Feb;43(1):113-119. doi: 10.1007/s00068-015-0556-2. Epub 2015 Aug 11.

Abstract

INTRODUCTION

In Europe, trauma admissions and in particular hip fractures are on the rise. In recent years, health care systems have placed particular emphasis, including financial incentives, on delivering patients quickly and safely to surgery. At our unit, we have observed that hip fracture patients appear to be at significant risk of mortality even up to a year following injury. This study reviews a consecutive population of hip fracture patients to identify predictors of excess risk.

MATERIALS AND METHODS

Four hundred and sixty-five consecutive patients were treated over a 2-year period at our district general hospital with no ward-based orthogeriatricians. Follow-up was for 1 year following hip fracture admission. Statistical analysis of variables and their influence on 1-year mortality were performed by calculating odd's ratio (OR) using a logistic regression model and a p value <0.05 was considered statistically significant.

RESULTS

Four patients were lost to follow-up, 18 patients (4.1 %) were managed conservatively, 16 were too unwell for surgery and their mortality rate at 1 year was 50 %. Following hip fracture, we found an overall 1-year mortality rate of 15.1 %. Patients with a time to surgery ≥36 h were at significantly increased risk of mortality even up to 1 year. We did not identify a further reduction in mortality in those operated on within 24 h. Raised ORs (p > 0.05) were found with increasing comorbidity, surgery type, independence on discharge, alcohol ingestion, history of smoking, readmission and several biochemical markers.

CONCLUSION

Minimising mortality risk, even over the longer term, should begin on admission with prompt optimisation of any acute medical or biochemical abnormalities, followed by early surgery and intensive rehabilitation to maintain patients' functional independence.

摘要

引言

在欧洲,创伤入院人数,尤其是髋部骨折患者人数呈上升趋势。近年来,医疗保健系统特别强调,包括提供经济激励措施,以便将患者快速、安全地送至手术室进行手术。在我们科室,我们观察到髋部骨折患者在受伤后长达一年的时间里似乎都面临着显著的死亡风险。本研究回顾了一组连续的髋部骨折患者,以确定额外风险的预测因素。

材料与方法

在我们地区综合医院,在没有病房骨科老年病医生的情况下,对连续465例患者进行了为期2年的治疗。对髋部骨折入院后的患者进行了1年的随访。通过使用逻辑回归模型计算比值比(OR),对变量及其对1年死亡率的影响进行统计分析,p值<0.05被认为具有统计学意义。

结果

4例患者失访,18例患者(4.1%)接受保守治疗,16例患者病情太重无法进行手术,其一年死亡率为50%。髋部骨折后,我们发现总体1年死亡率为15.1%。手术时间≥36小时的患者,即使在长达1年的时间里,死亡风险也显著增加。我们没有发现24小时内接受手术的患者死亡率有进一步降低。随着合并症、手术类型增加、出院时的独立性、饮酒、吸烟史、再次入院以及几个生化指标的增加,OR值升高(p>0.05)。

结论

即使在较长时期内,将死亡风险降至最低也应从入院时开始,迅速优化任何急性医疗或生化异常情况,随后尽早进行手术和强化康复,以维持患者的功能独立性。

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