Suppr超能文献

455例巨大食管裂孔疝患者20年的修补耐久性

Durability of giant hiatus hernia repair in 455 patients over 20 years.

作者信息

Le Page P A, Furtado R, Hayward M, Law S, Tan A, Vivian S J, Van der Wall H, Falk G L

机构信息

1 Concord Repatriation General Hospital, NSW , Australia.

2 University of Sydney, NSW , Australia.

出版信息

Ann R Coll Surg Engl. 2015 Apr;97(3):188-93. doi: 10.1308/003588414X14055925060839.

Abstract

INTRODUCTION

The surgical management of symptomatic giant hiatus hernia (GHH) aims to improve quality of life (QoL) and reduce the risk of life threatening complications. Previous reports are predominantly those with small sample sizes and short follow-up periods. The present study sought to assess a large cohort of patients for recurrence and QoL over a longer time period.

METHODS

This was a follow-up study of a prospectively collected database of 455 consecutive patients. Primary repair of GHH was evaluated by endoscopy/barium meal for recurrence and a standardised symptom questionnaire for QoL. Recurrence was assessed for size, elapsed time, oesophagitis and symptoms.

RESULTS

Objective and subjective review was achieved in 91.9% and 68.6% of patients. The median age was 69 years (range: 15-93 years) and 64% were female. Laparoscopic repair was completed in 95% (mesh in 6% and Collis gastroplasty in 7%). The 30-day mortality rate was 0.9%. The proportion of patients alive at five and ten years were 90% and 75% respectively. Postoperative QoL scores improved from a mean of 95 to 111 (p<0.01) and were stable over time (112 at 10 years). The overall recurrence rate was 35.6% (149/418) at 42 months; this was 11.5% (48/418) for hernias >2cm and 24.2% (101/418) for <2cm. The rate of new recurrence at 0-1 years was 13.7% (>2cm = 3.4%, <2cm = 10.3%), at 1-5 years it was 30.8% (>2cm = 9.5%, <2cm = 21.3%), at 5-10 years it was 40.1% (>2cm = 13.8%, <2cm = 26.3%) and at over 10 years it was 50.0% (>2cm = 25.0%, <2cm = 25.0%). Recurrence was associated with oesophagitis but not decreased QoL. Revision surgery was required in 4.8% of cases (14.8% with recurrence). There were no interval major GHH complications.

CONCLUSIONS

Surgery has provided sustained QoL improvements irrespective of recurrence. Recurrence occurred progressively over ten years and may predispose to oesophagitis.

摘要

引言

有症状的巨大食管裂孔疝(GHH)的外科治疗旨在改善生活质量(QoL)并降低危及生命的并发症风险。以往的报告大多样本量小且随访期短。本研究旨在评估一大群患者在较长时间段内的复发情况和生活质量。

方法

这是一项对前瞻性收集的455例连续患者数据库的随访研究。通过内镜检查/钡餐评估GHH的初次修复情况以判断复发,并使用标准化症状问卷评估生活质量。对复发的大小、时间、食管炎和症状进行评估。

结果

分别有91.9%和68.6%的患者完成了客观和主观评估。中位年龄为69岁(范围:15 - 93岁),64%为女性。95%的患者完成了腹腔镜修复(6%使用补片,7%进行科利斯胃成形术)。30天死亡率为0.9%。5年和10年存活患者的比例分别为90%和75%。术后生活质量评分从平均95分提高到111分(p<0.01),且随时间保持稳定(10年时为112分)。42个月时总体复发率为35.6%(149/418);疝囊>2cm者复发率为11.5%(48/418),<2cm者为24.2%(101/418)。0 - 1年新复发率为13.7%(>2cm = 3.4%,<2cm = 10.3%),1 - 5年为30.8%(>2cm = 9.5%,<2cm = 21.3%),5 - 10年为40.1%(>2cm = 13.8%,<2cm = 26.3%),超过10年为50.0%(>2cm = 25.0%,<2cm = 25.0%)。复发与食管炎相关,但与生活质量下降无关。4.8%的病例需要再次手术(复发患者中为14.8%)。期间未发生重大GHH并发症。

结论

无论是否复发,手术均持续改善了生活质量。复发在十年间逐渐发生,且可能易导致食管炎。

相似文献

1
Durability of giant hiatus hernia repair in 455 patients over 20 years.
Ann R Coll Surg Engl. 2015 Apr;97(3):188-93. doi: 10.1308/003588414X14055925060839.
2
Medium-term durability of giant hiatus hernia repair without mesh.
Ann R Coll Surg Engl. 2016 Sep;98(7):450-5. doi: 10.1308/rcsann.2016.0156. Epub 2016 Jul 7.
5
Laparoscopic management of large hiatus hernia: five-year cohort study and comparison of mesh-augmented versus standard crura repair.
Surg Endosc. 2016 Dec;30(12):5404-5409. doi: 10.1007/s00464-016-4897-7. Epub 2016 Apr 29.
6
Laparoscopic repair of giant hiatus hernia: prosthesis is not required for successful outcome.
Surg Endosc. 2013 Feb;27(2):618-23. doi: 10.1007/s00464-012-2501-3. Epub 2012 Aug 28.
7
Impact of Laparoscopic Repair of Large Hiatus Hernia on Quality of Life: Observational Cohort Study.
Dig Surg. 2019;36(5):402-408. doi: 10.1159/000490359. Epub 2018 Jun 20.
8
Laparoscopic anterior 90 degree fundoplication for reflux or large hiatus hernia.
ANZ J Surg. 2008 Mar;78(3):123-7. doi: 10.1111/j.1445-2197.2007.04385.x.

引用本文的文献

1
Unilateral Lung Agenesis: A Systematic Review of Prevalence, Anatomical Variants, and Clinical Implications.
Diagnostics (Basel). 2025 Sep 8;15(17):2272. doi: 10.3390/diagnostics15172272.
2
Long-term durability and temporal pattern of revisional surgery of laparoscopic large hiatal hernia repair.
Updates Surg. 2025 Apr;77(2):419-425. doi: 10.1007/s13304-025-02070-y. Epub 2025 Jan 23.
3
Impact of laparoscopic repair on type III/IV giant paraesophageal hernias: a single-center experience.
Hernia. 2023 Dec;27(6):1555-1570. doi: 10.1007/s10029-023-02851-7. Epub 2023 Aug 29.
4
Comment on "Sutured Versus Mesh-augmented Hiatus Hernia Repair: A Systematic Review and Meta-analysis of Randomized Controlled Trials".
Ann Surg Open. 2022 Jun 17;3(3):e173. doi: 10.1097/AS9.0000000000000173. eCollection 2022 Sep.
5
Dyspnoea improves following composite repair of giant paraoesophageal hernia.
Ann R Coll Surg Engl. 2023 Jul;105(6):523-527. doi: 10.1308/rcsann.2022.0124. Epub 2022 Nov 14.
7
Giant paraesophageal hernia: What do we really know?
JTCVS Tech. 2020 Aug 13;3:367-372. doi: 10.1016/j.xjtc.2020.08.021. eCollection 2020 Sep.
8
Preoperative botulinum toxin type A: A case report of a proposed new strategy for giant hiatal hernia management.
Clin Case Rep. 2020 Oct 27;8(12):3412-3415. doi: 10.1002/ccr3.3416. eCollection 2020 Dec.
9
Long-term outcomes following surgical repair of giant paraoesophageal hiatus hernia.
Surg Endosc. 2019 Jun;33(6):1846-1853. doi: 10.1007/s00464-018-6463-y. Epub 2018 Nov 7.
10
Treatment of giant paraesophageal hernia: pro laparoscopic approach.
Hernia. 2018 Dec;22(6):909-919. doi: 10.1007/s10029-017-1706-8. Epub 2017 Nov 25.

本文引用的文献

1
A technique for the laparoscopic repair of paraoesophageal hernia without mesh.
J Gastrointest Surg. 2014 Apr;18(4):851-7; discussion 857. doi: 10.1007/s11605-013-2397-9. Epub 2013 Nov 19.
2
Laparoscopic repair of giant hiatus hernia: prosthesis is not required for successful outcome.
Surg Endosc. 2013 Feb;27(2):618-23. doi: 10.1007/s00464-012-2501-3. Epub 2012 Aug 28.
3
Outcomes of surgical management of symptomatic large recurrent hiatus hernia.
Surg Endosc. 2012 Jun;26(6):1501-8. doi: 10.1007/s00464-011-2072-8. Epub 2011 Dec 17.
4
The laparoscopic approach to paraesophageal hernia repair.
J Gastrointest Surg. 2012 Feb;16(2):417-26. doi: 10.1007/s11605-011-1690-8. Epub 2011 Dec 9.
5
Repair of giant paraesophageal hernias routinely produces improvement in respiratory function.
J Thorac Cardiovasc Surg. 2012 Feb;143(2):398-404. doi: 10.1016/j.jtcvs.2011.10.025. Epub 2011 Nov 20.
6
Quality of life after collis gastroplasty for short esophagus in patients with paraesophageal hernia.
Ann Thorac Surg. 2011 Nov;92(5):1854-60; discussion 1860-1. doi: 10.1016/j.athoracsur.2011.06.030. Epub 2011 Sep 25.
7
Laparoscopic repair of large hiatal hernia: impact on dyspnoea.
Surg Endosc. 2011 Nov;25(11):3620-6. doi: 10.1007/s00464-011-1768-0. Epub 2011 Jun 3.
8
Laparoscopic versus open repair of paraesophageal hernia: the second decade.
J Am Coll Surg. 2011 May;212(5):813-20. doi: 10.1016/j.jamcollsurg.2011.01.060. Epub 2011 Mar 23.
10
Giant hiatal hernia.
Ann Thorac Surg. 2010 Jun;89(6):S2168-73. doi: 10.1016/j.athoracsur.2010.03.022.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验