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[根除脊髓灰质炎——实现目标的重要一步]

[POLIOMYELITIS ERADICATION--ONE STEP TO ACHIEVE THE GOAL].

作者信息

Ljubin-Sternak Sunčanica, Kaić Bernard, Vilibić-Čavlek Tatjana, Mlinarić-Galinović Gordana

出版信息

Acta Med Croatica. 2014 Dec;68(4-5):327-35.

Abstract

Poliomyelitis is a very old disease of humans, caused by poliovirus. With appearance of the epidemics in the 20th century, poliomyelitis became a global public health issue. In 1988, the World Health Organization started a campaign for global eradication of poliomyelitis and till now poliomyelitis cases have been reduced by more than 99%. In Croatia, the introduction of vaccination in 1961 resulted in dramatic reduction of paralytic disease. The European region, including Croatia was certified polio free in 2002. However, the final goal of the "polio-free world" has not yet been reached. To reinforce the campaign, the global polio eradication initiative has come up with the Polio Eradication & Endgame Strategic Plan 2013-2018 with detailed program how to resolve the main challenges: (a) continued transmission of wild polioviruses in endemic reservoirs; (b) reinfection of polio-free areas; and (c) outbreaks due to the circulating vaccine-derived polioviruses (cVDPV). Global oral polio vaccine cessation will follow, with the introduction of universal use of inactivated polio vaccine.

摘要

脊髓灰质炎是一种古老的人类疾病,由脊髓灰质炎病毒引起。随着20世纪疫情的出现,脊髓灰质炎成为一个全球公共卫生问题。1988年,世界卫生组织发起了全球根除脊髓灰质炎运动,迄今为止,脊髓灰质炎病例已减少了99%以上。在克罗地亚,1961年引入疫苗接种后,麻痹性疾病大幅减少。包括克罗地亚在内的欧洲地区于2002年被认证为无脊髓灰质炎地区。然而,“无脊髓灰质炎世界”的最终目标尚未实现。为加强该运动,全球根除脊髓灰质炎行动推出了《2013 - 2018年脊髓灰质炎根除与终结战略计划》,其中包含了如何应对主要挑战的详细方案:(a) 野生脊髓灰质炎病毒在流行地区持续传播;(b) 无脊髓灰质炎地区再次感染;以及(c) 由循环疫苗衍生脊髓灰质炎病毒(cVDPV)引起的疫情。随着通用灭活脊髓灰质炎疫苗的引入,全球口服脊髓灰质炎疫苗将停止使用。

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