Department of Cardiac, Thoracic and Vascular Sciences, Hygiene and Public Health Unit, University of Padua, Via Loredan, 18, 35121, Padua, Italy.
EuroHealth Net, Veneto Region Health Directorate, Veneto, Italy.
Aging Clin Exp Res. 2019 Jan;31(1):145-150. doi: 10.1007/s40520-018-0968-z. Epub 2018 May 15.
To assess the burden of herpes zoster (HZ) by analyzing HZ-related hospital admissions.
We conducted a population-based descriptive cross-sectional study on all hospitalizations for HZ among the resident population admitted to all public and accredited private hospitals in the Veneto Region (north-east Italy) during the years 2008-2016. HZ hospitalizations were identified from the International Classification of Diseases codes in the hospital discharge records.
During the period considered, we identified 3566 HZ-associated admissions, 194 (5.4%) of which were readmissions within 30 days. A complicated HZ diagnosis was mentioned for 44.4% of the patients admitted once and for 65.9% of those admitted twice. In the sample as a whole, 27.0% of patients had at least one comorbidity. Overall, our analysis revealed a gradual increase in hospitalizations with age for both genders, reaching a hospitalization rate for the population over 80 years old of 51.2 × 100,000 for males and 52.8 × 100,000 for females. The average hospitalization rate for HZ-related conditions during the years 2008-2016 was 7.7 per 100,000 population. Postherpetic neuralgia was diagnosed in 8.2% of hospitalizations, with no difference between the genders. The estimated overall cost of HZ-related conditions was approximately €2.7 million a year.
This study suggests that the burden of HZ and its impact on quality of life are of critical relevance to public health decision-making.
通过分析带状疱疹（HZ）相关住院治疗情况来评估 HZ 的负担。
我们对 2008 年至 2016 年期间所有因 HZ 住院的居民进行了一项基于人群的描述性横断面研究，这些居民在威尼托地区（意大利东北部）的所有公立和私立认证医院住院。HZ 住院治疗是从医院出院记录中的国际疾病分类代码中确定的。
在所考虑的期间内，我们确定了 3566 例 HZ 相关住院治疗，其中 194 例（5.4%）在 30 天内再次住院。初次住院的患者中有 44.4%被诊断为复杂 HZ，再次住院的患者中有 65.9%被诊断为复杂 HZ。在整个样本中，27.0%的患者至少有一种合并症。总体而言，我们的分析显示，男女患者的住院率均随年龄的增长而逐渐增加，80 岁以上人群的住院率为男性 51.2×100,000，女性 52.8×100,000。2008 年至 2016 年期间，与 HZ 相关的疾病的平均住院率为每 10 万人 7.7 例。8.2%的住院患者被诊断为带状疱疹后神经痛，男女之间无差异。与 HZ 相关疾病的总估计费用约为每年 270 万欧元。
本研究表明，HZ 的负担及其对生活质量的影响对公共卫生决策具有至关重要的意义。
