脂肪酸和微量营养素在健康老龄化中的作用:在欧洲老年人饮食调查背景下对随机对照试验的系统评价

Role of fatty acids and micronutrients in healthy ageing: a systematic review of randomised controlled trials set in the context of European dietary surveys of older adults.

作者信息

Ruxton C H S, Derbyshire E, Toribio-Mateas M

机构信息

Nutrition Communications, Cupar, UK.

Nutritional Insight Ltd, Epsom, Surrey, UK.

出版信息

J Hum Nutr Diet. 2016 Jun;29(3):308-24. doi: 10.1111/jhn.12335. Epub 2015 Aug 18.

Abstract

BACKGROUND

Ageing is a multifaceted and inevitable process involving a decline in health and well-being that could be ameliorated by dietary modification. We review and discuss the evidence for nutritional interventions that may support healthy ageing.

METHODS

The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were used to identify randomised controlled trials investigating the role(s) of fatty acids and micronutrients in relation to markers of healthy ageing.

RESULTS

European dietary surveys suggest that diets in elderly people are generally high in saturated fat, whereas intakes of vitamin D, magnesium, potassium, zinc and copper are below recommended levels. Thirty-four studies meeting the criteria were found, with 12 of these investigating the role of fatty acids and 22 considering intakes of micronutrients in relation to healthy ageing. Overall, these studies suggested that certain nutrients were consistent with healthy ageing; for example, omega-3 fatty acids were helpful for cognitive health, whereas combinations of calcium, vitamin D and K were linked with better bone health.

CONCLUSIONS

Vitamin, mineral and fatty acid intakes are in need of improvement to help elderly populations achieve optimal diet quality and support healthy ageing. This could involve the judicious use of supplements alongside dietary advice. Additional research is needed to determine optimal nutrient doses, combinations and forms in relation to desired health outcomes.

摘要

背景

衰老 是一个多方面的、不可避免的过程,涉及健康和幸福感的下降,而饮食调整可能会改善这种情况。我们回顾并讨论了可能支持健康衰老的营养干预措施的证据。

方法

采用系统评价和Meta分析的首选报告项目(PRISMA)指南来识别研究脂肪酸和微量营养素在健康衰老标志物方面作用的随机对照试验。

结果

欧洲饮食调查表明,老年人的饮食中饱和脂肪含量普遍较高,而维生素D、镁、钾、锌和铜的摄入量低于推荐水平。共找到34项符合标准的研究,其中12项研究了脂肪酸的作用,22项研究了微量营养素摄入量与健康衰老的关系。总体而言,这些研究表明某些营养素与健康衰老相符;例如,ω-3脂肪酸有助于认知健康,而钙、维生素D和K的组合与更好的骨骼健康有关。

结论

需要改善维生素、矿物质和脂肪酸的摄入量,以帮助老年人群实现最佳饮食质量并支持健康衰老。这可能包括在饮食建议的同时明智地使用补充剂。需要进一步研究以确定与期望的健康结果相关的最佳营养素剂量、组合和形式。

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