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尼日利亚高血压预防研究:对尼日利亚东南部乌穆阿希亚明显健康成年人的高血压前期及其关联的研究。

Towards prevention of hypertension in Nigeria: a study of prehypertension and its associations among apparently healthy adults in Umuahia, South-East Nigeria.

作者信息

Okwuonu Chimezie Godswill, Ngoka Stanley Chidozie, Chimezie Oluchi Justina, Eze Tochukwu Hycinth, Uwanurochi Kelechukwu, Mbanaso Augustus Ugwunna

机构信息

Nephrology Unit, Department of Internal Medicine, Federal Medical Centre, Umuahia, Abia State, Nigeria.

Nephrology Unit, Department of Internal Medicine, Federal Medical Centre, Owerri, Imo State, Nigeria.

出版信息

Int J Prev Med. 2015 Jul 13;6:61. doi: 10.4103/2008-7802.160968. eCollection 2015.

Abstract

BACKGROUND

The prevalence of hypertension is on the increase in Nigeria. Prehypertension is considered a precursor of hypertension and a predictor of excessive cardiovascular risk. Identifying individuals with prehypertension and initiating effective measures will aid in reducing the incidence and prevalence of hypertension in our environment. The aim of this study was to quantify the magnitude of prehypertension and determine its associations among adults in a representative semi-urban Nigerian population.

METHODS

A cross-sectional study which was carried out in a semi-urban setting in Southeast Nigeria. Blood pressure (BP) was measured using the standard methods. A cardiovascular risk factor screening based on physical characteristics, individual medical, and family history of participants was done.

RESULTS

There were a total of 389 participants comprising 223 (57.3%) males and 116 (42.7%) females; male:female ratio been 1.9:1. The prevalence of prehypertension and hypertension were 45.5% and 37.8%, respectively. Males were significantly more likely to have prehypertension than females (61% vs. 39% respectively; OR = 1.32, P = 0.03). There was a weak positive significant correlation between age and both systolic (r = 0.16, P < 0.01) and diastolic (r = 0.12, P = 0.02) blood pressures. Up to 72.6% of individuals with prehypertension have abnormal body mass index (BMI). While up to 8.5% of the participants had a family history of cardiovascular disease, 20.3%, and 17.3% had a history of significant intake of alcohol and smoking, respectively.

CONCLUSIONS

The prevalence of prehypertension in the community was high. It was associated with increasing age, male gender, and increasing BMI. Interventions at this stage may aid in stemming the rising prevalence of hypertension in our environment.

摘要

背景

在尼日利亚,高血压的患病率呈上升趋势。高血压前期被视为高血压的先兆以及心血管风险过高的预测指标。识别高血压前期个体并采取有效措施将有助于降低我们所处环境中高血压的发病率和患病率。本研究的目的是量化尼日利亚一个具有代表性的半城市成年人群中高血压前期的程度,并确定其相关性。

方法

在尼日利亚东南部的一个半城市地区开展了一项横断面研究。采用标准方法测量血压。基于参与者的身体特征、个人病史和家族病史进行心血管危险因素筛查。

结果

共有389名参与者,其中男性223名(57.3%),女性116名(42.7%);男女比例为1.9:1。高血压前期和高血压的患病率分别为45.5%和37.8%。男性患高血压前期的可能性显著高于女性(分别为61%和39%;OR = 1.32,P = 0.03)。年龄与收缩压(r = 0.16,P < 0.01)和舒张压(r = 0.12,P = 0.02)之间存在微弱的正相关。高达72.6%的高血压前期个体体重指数(BMI)异常。虽然高达8.5%的参与者有心血管疾病家族史,但分别有20.3%和17.3%的参与者有大量饮酒和吸烟史。

结论

该社区高血压前期的患病率很高。它与年龄增长、男性性别以及BMI增加有关。在此阶段进行干预可能有助于遏制我们所处环境中高血压患病率的上升。

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