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2003 - 2013年英国国家卫生研究院卫生技术评估项目的影响:多方法评估

The impact of the National Institute for Health Research Health Technology Assessment programme, 2003-13: a multimethod evaluation.

作者信息

Guthrie Susan, Bienkowska-Gibbs Teresa, Manville Catriona, Pollitt Alexandra, Kirtley Anne, Wooding Steven

机构信息

RAND Europe, Cambridge, UK.

出版信息

Health Technol Assess. 2015 Aug;19(67):1-291. doi: 10.3310/hta19670.

Abstract

BACKGROUND

The National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme supports research tailored to the needs of NHS decision-makers, patients and clinicians. This study reviewed the impact of the programme, from 2003 to 2013, on health, clinical practice, health policy, the economy and academia. It also considered how HTA could maintain and increase its impact.

METHODS

Interviews (n = 20): senior stakeholders from academia, policy-making organisations and the HTA programme. Bibliometric analysis: citation analysis of publications arising from HTA programme-funded research. Researchfish survey: electronic survey of all HTA grant holders. Payback case studies (n = 12): in-depth case studies of HTA programme-funded research.

RESULTS

We make the following observations about the impact, and routes to impact, of the HTA programme: it has had an impact on patients, primarily through changes in guidelines, but also directly (e.g. changing clinical practice); it has had an impact on UK health policy, through providing high-quality scientific evidence - its close relationships with the National Institute for Health and Care Excellence (NICE) and the National Screening Committee (NSC) contributed to the observed impact on health policy, although in some instances other organisations may better facilitate impact; HTA research is used outside the UK by other HTA organisations and systematic reviewers - the programme has an impact on HTA practice internationally as a leader in HTA research methods and the funding of HTA research; the work of the programme is of high academic quality - the Health Technology Assessment journal ensures that the vast majority of HTA programme-funded research is published in full, while the HTA programme still encourages publication in other peer-reviewed journals; academics agree that the programme has played an important role in building and retaining HTA research capacity in the UK; the HTA programme has played a role in increasing the focus on effectiveness and cost-effectiveness in medicine - it has also contributed to increasingly positive attitudes towards HTA research both within the research community and the NHS; and the HTA focuses resources on research that is of value to patients and the UK NHS, which would not otherwise be funded (e.g. where there is no commercial incentive to undertake research). The programme should consider the following to maintain and increase its impact: providing targeted support for dissemination, focusing resources when important results are unlikely to be implemented by other stakeholders, particularly when findings challenge vested interests; maintaining close relationships with NICE and the NSC, but also considering other potential users of HTA research; maintaining flexibility and good relationships with researchers, giving particular consideration to the Technology Assessment Report (TAR) programme and the potential for learning between TAR centres; maintaining the academic quality of the work and the focus on NHS need; considering funding research on the short-term costs of the implementation of new health technologies; improving the monitoring and evaluation of whether or not patient and public involvement influences research; improve the transparency of the priority-setting process; and continuing to monitor the impact and value of the programme to inform its future scientific and administrative development.

摘要

背景

英国国家卫生研究院(NIHR)卫生技术评估(HTA)项目支持开展符合英国国家医疗服务体系(NHS)决策者、患者及临床医生需求的研究。本研究回顾了该项目在2003年至2013年期间对健康、临床实践、卫生政策、经济及学术界的影响。研究还探讨了HTA如何维持并增强其影响力。

方法

访谈(n = 20):来自学术界、政策制定组织及HTA项目的高级利益相关者。文献计量分析:对HTA项目资助研究产生的出版物进行引文分析。Researchfish调查:对所有HTA资助获得者进行电子调查。回报案例研究(n = 12):对HTA项目资助研究进行深入案例研究。

结果

我们对HTA项目的影响及影响途径有以下观察结果:该项目对患者产生了影响,主要是通过指南的变化,但也有直接影响(如改变临床实践);通过提供高质量的科学证据,它对英国卫生政策产生了影响——其与英国国家卫生与临床优化研究所(NICE)及国家筛查委员会(NSC)的密切关系促成了对卫生政策的显著影响,尽管在某些情况下其他组织可能更有助于产生影响;HTA研究被其他HTA组织及系统评价者在英国以外使用——该项目作为HTA研究方法及HTA研究资助方面的领导者,对国际HTA实践产生了影响;该项目的工作具有很高的学术质量——《卫生技术评估》期刊确保了绝大多数HTA项目资助的研究得以全文发表,而HTA项目仍鼓励在其他同行评审期刊上发表;学术界一致认为该项目在英国建立和保留HTA研究能力方面发挥了重要作用;HTA项目在增强对医学有效性和成本效益的关注方面发挥了作用——它还促成了研究界和NHS内部对HTA研究越来越积极的态度;HTA将资源集中于对患者和英国NHS有价值的研究,否则这些研究将得不到资助(例如在没有商业动机进行研究的情况下)。该项目应考虑以下方面以维持并增强其影响力:提供有针对性的传播支持,在其他利益相关者不太可能实施重要结果时集中资源,特别是当研究结果挑战既得利益时;与NICE和NSC保持密切关系,但也要考虑HTA研究的其他潜在用户;与研究人员保持灵活性和良好关系,特别考虑技术评估报告(TAR)项目以及TAR中心之间的学习潜力;保持工作的学术质量并关注NHS的需求;考虑资助关于新卫生技术实施短期成本的研究;改进对患者和公众参与是否影响研究的监测和评估;提高优先事项设定过程的透明度;并继续监测该项目的影响和价值,以为其未来的科学和行政发展提供信息。

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