Ghayempour Soraya, Montazer Majid, Mahmoudi Rad Mahnaz
Textile Engineering Department, Functional Fibrous Structures & Environmental Enhancement (FFSEE), Amirkabir University of Technology, Tehran, Iran.
Textile Engineering Department, Functional Fibrous Structures & Environmental Enhancement (FFSEE), Amirkabir University of Technology, Tehran, Iran.
Int J Biol Macromol. 2015 Nov;81:514-20. doi: 10.1016/j.ijbiomac.2015.08.041. Epub 2015 Aug 24.
Tragacanth gum as a biocompatible and biodegradable polymer with good properties including emulsifying, viscosity and cross-linking ability can be used as the wall material in encapsulation of different compounds, specifically plant extracts. In this paper, for the first time, Tragacanth gum was used to produce nanocapsules containing plant extract through microemulsion method. The effect of different parameters on the average size of prepared nanocapsules in presence of aluminum and calcium chloride through ultrasonic and magnetic stirrer was investigated. The high efficient nanocapsules were prepared with spherical shape and smooth surface. The average size of nanocapsules prepared through ultrasonic using aluminum chloride (22nm) was smaller than other products. The structure of prepared nanocapsules was studied by FT-IR spectroscopy. Antimicrobial activity of different nanocapsules against Escherichia coli, Staphylococcus aureus and Candida albicans was investigated by shake flask method during their release showed 100% microbial reduction after 12h stirring.
黄芪胶作为一种具有良好性能（包括乳化、增稠和交联能力）的生物相容性和可生物降解聚合物，可作为不同化合物（特别是植物提取物）包封的壁材。本文首次采用微乳液法，用黄芪胶制备了含植物提取物的纳米胶囊。研究了在氯化铝和氯化钙存在下，通过超声和磁力搅拌，不同参数对所制备纳米胶囊平均粒径的影响。制备出了具有球形和光滑表面的高效纳米胶囊。用氯化铝通过超声制备的纳米胶囊平均粒径（22nm）小于其他产品。通过傅里叶变换红外光谱（FT-IR）对所制备纳米胶囊的结构进行了研究。采用摇瓶法研究了不同纳米胶囊对大肠杆菌、金黄色葡萄球菌和白色念珠菌的抗菌活性，结果表明，搅拌12h后纳米胶囊释放过程中微生物减少率达100%。
