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我们应如何选择“最佳”胚胎?英国生育协会和临床胚胎学家协会联合评论

How should we choose the 'best' embryo? A commentary on behalf of the British Fertility Society and the Association of Clinical Embryologists.

作者信息

Bolton Virginia N, Leary Christine, Harbottle Stephen, Cutting Rachel, Harper Joyce C

机构信息

a Assisted Conception Unit, Guy's & St Thomas' NHS Foundation Trust, Guy's Hospital , London , UK.

b Hull IVF Unit, The Women & Children's Hospital, Hull Royal Infirmary , Hull , UK.

出版信息

Hum Fertil (Camb). 2015 Sep;18(3):156-64. doi: 10.3109/14647273.2015.1072646. Epub 2015 Aug 27.

DOI:10.3109/14647273.2015.1072646
PMID:26313607
Abstract

Embryo selection to improve pregnancy rates remains a significant challenge in IVF. Non-invasive and invasive methods of embryo selection include morphological assessment, metabolomics, time-lapse imaging and preimplantation genetic screening. To date, none has been shown conclusively to yield improved implantation and live birth rates. This review summarises current understanding of methods for embryo selection.

摘要

在体外受精(IVF)中,选择胚胎以提高妊娠率仍然是一项重大挑战。胚胎选择的非侵入性和侵入性方法包括形态学评估、代谢组学、延时成像和植入前基因筛查。迄今为止,尚无一种方法能确凿地证明可提高着床率和活产率。本综述总结了目前对胚胎选择方法的认识。

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How should we choose the 'best' embryo? A commentary on behalf of the British Fertility Society and the Association of Clinical Embryologists.我们应如何选择“最佳”胚胎?英国生育协会和临床胚胎学家协会联合评论
Hum Fertil (Camb). 2015 Sep;18(3):156-64. doi: 10.3109/14647273.2015.1072646. Epub 2015 Aug 27.
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Assessment of embryo morphology and developmental dynamics by time-lapse microscopy: is there a relation to implantation and ploidy?通过延时显微镜评估胚胎形态和发育动力学:其与着床及倍性是否存在关联?
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Artificial intelligence in human in vitro fertilization and embryology.人工智能在人类体外受精和胚胎学中的应用。
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[Does embryo morphology constitute a reliable criterion for embryo selection?].[胚胎形态学是否构成胚胎选择的可靠标准?]
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Focus on time-lapse analysis: blastocyst collapse and morphometric assessment as new features of embryo viability.关注时间推移分析:囊胚皱缩和形态评估作为胚胎活力的新特征。
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Experience of more than 100 preimplantation genetic diagnosis cycles for monogenetic diseases using whole genome amplification and linkage analysis in a single centre.在单一中心使用全基因组扩增和连锁分析进行100多个单基因疾病植入前基因诊断周期的经验。
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Improved implantation rates of day 3 embryo transfers with the use of an automated time-lapse-enabled test to aid in embryo selection.使用具备自动延时功能的测试辅助胚胎选择,可提高第3天胚胎移植的着床率。
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