Bolton Virginia N, Leary Christine, Harbottle Stephen, Cutting Rachel, Harper Joyce C
a Assisted Conception Unit, Guy's & St Thomas' NHS Foundation Trust, Guy's Hospital , London , UK.
b Hull IVF Unit, The Women & Children's Hospital, Hull Royal Infirmary , Hull , UK.
Hum Fertil (Camb). 2015 Sep;18(3):156-64. doi: 10.3109/14647273.2015.1072646. Epub 2015 Aug 27.
Embryo selection to improve pregnancy rates remains a significant challenge in IVF. Non-invasive and invasive methods of embryo selection include morphological assessment, metabolomics, time-lapse imaging and preimplantation genetic screening. To date, none has been shown conclusively to yield improved implantation and live birth rates. This review summarises current understanding of methods for embryo selection.
在体外受精(IVF)中,选择胚胎以提高妊娠率仍然是一项重大挑战。胚胎选择的非侵入性和侵入性方法包括形态学评估、代谢组学、延时成像和植入前基因筛查。迄今为止,尚无一种方法能确凿地证明可提高着床率和活产率。本综述总结了目前对胚胎选择方法的认识。