Soueidan Michael, Bartlett Susan J, Noureldin Yasser A, Andersen Ross E, Andonian Sero
Division of Urology, McGill University Health Centre, Montreal, QC;
Faculty of Medicine, McGill University; Division of Clinical Epidemiology, McGill University Health Centre, Montreal, QC;
Can Urol Assoc J. 2015 Jul-Aug;9(7-8):257-62. doi: 10.5489/cuaj.2879.
We explore relationships between selected lifestyle factors and recent (≤6 months) symptomatic urolithiasis (RSU).
Surveys querying socio-demographic, medical history, physical activity, diet and smoking were administered to a convenience sample of stone clinic patients at a tertiary care hospital. Leisure time physical activity (LTPA) was assessed with the International Physical Activity Questionnaire (long form). Multivariate logistic regression was used to identify associations between risk factors and RSU.
Of the 163 participants, most were male (64%) and white (78%), with a mean (standard deviation) age of 56.3 (14.2) years. The mean body mass index (BMI) was 27.3 (5.4) kg/m(2) and 57 (35%) patients reported RSU. No significant (p < 0.05) differences were observed between participants with and without RSU in age, sex, ethnicity, BMI, or diet. Of the cohort, 52 (35%) participants met physical activity guidelines for walking (29%), moderate (27%) or vigorous activity (29%). LTPA did not differ significantly by RSU status. Compared to those without RSU, participants with RSU had higher rates of smoking (7% vs. 21%, p = 0.02 and had 8.5 (95% confidence interval 2.2-32.2) times the odds of being current smokers after controlling for sex, diet, and LTPA.
Physical inactivity and smoking are common among stone clinic patients, though LPTA was not associated with RSU. Study limitations include its small sample size, selection bias, and reliance on self-reported RSU (recall bias). In addition, participants may have already been following dietary recommendations to prevent urolithiasis recurrence. Nonetheless, current smoking was a potent predictor of RSU. When desired, smokers should be referred for smoking cessation.
我们探讨了特定生活方式因素与近期（≤6个月）有症状的尿路结石（RSU）之间的关系。
对一家三级护理医院结石门诊患者的便利样本进行了调查，询问社会人口统计学、病史、身体活动、饮食和吸烟情况。休闲时间身体活动（LTPA）通过国际身体活动问卷（长表）进行评估。多因素逻辑回归用于确定风险因素与RSU之间的关联。
163名参与者中，大多数为男性（64%）和白人（78%），平均（标准差）年龄为56.3（14.2）岁。平均体重指数（BMI）为27.3（5.4）kg/m²，57名（35%）患者报告有RSU。有和没有RSU的参与者在年龄、性别、种族、BMI或饮食方面未观察到显著（p<0.05）差异。在该队列中，52名（35%）参与者达到了步行（29%）、中等强度（27%）或剧烈活动（29%）的身体活动指南要求。LTPA在有无RSU状态之间无显著差异。与没有RSU的参与者相比，有RSU的参与者吸烟率更高（7%对21%，p = 0.02），在控制性别、饮食和LTPA后，当前吸烟者的几率是其8.5倍（95%置信区间2.2 - 32.2）。
身体活动不足和吸烟在结石门诊患者中很常见，尽管LTPA与RSU无关。研究局限性包括样本量小、选择偏倚以及依赖自我报告的RSU（回忆偏倚）。此外，参与者可能已经遵循饮食建议以预防尿路结石复发。尽管如此，当前吸烟是RSU的一个有力预测因素。如有需要，应建议吸烟者戒烟。
