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年龄和症状持续时间对神经根型颈椎病患者单节段显微镜下前路颈椎间盘切除融合术手术疗效的影响

Impact of Age and Duration of Symptoms on Surgical Outcome of Single-Level Microscopic Anterior Cervical Discectomy and Fusion in the Patients with Cervical Spondylotic Radiculopathy.

作者信息

Omidi-Kashani Farzad, Ghayem Hasankhani Ebrahim, Ghandehari Reza

机构信息

Orthopedic Research Center, Orthopedic Department, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad 913791-3316, Iran.

Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad 913791-3316, Iran.

出版信息

Neurosci J. 2014;2014:808596. doi: 10.1155/2014/808596. Epub 2014 Sep 30.

DOI:10.1155/2014/808596
PMID:26317110
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4437266/
Abstract

We aim to evaluate the impact of age and duration of symptoms on surgical outcome of the patients with cervical spondylotic radiculopathy (CSR) who had been treated by single-level microscopic anterior cervical discectomy and fusion (ACDF). We retrospectively evaluated 68 patients (48 female and 20 male) with a mean age of 41.2 ± 4.3 (ranged from 24 to 72 years old) in our Orthopedic Department, Imam Reza Hospital. They were followed up for 31.25 ± 4.1 months (ranged from 25 to 65 months). Pain and disability were assessed by Visual Analogue Scale (VAS) and Neck Disability Index (NDI) questionnaires in preoperative and last follow-up visits. Functional outcome was eventually evaluated by Odom's criteria. Surgery could significantly improve pain and disability from preoperative 6.2 ± 1.4 and 22.2 ± 6.2 to 3.5 ± 2.0 and 8.7 ± 5.2 (1-21) at the last follow-up visit, respectively. Satisfactory outcomes were observed in 89.7%. Symptom duration of more and less than six months had no effect on surgical outcome, but the results showed a statistically significant difference in NDI improvement in favor of the patients aged more than 45 years (P = 0.032), although pain improvement was similar in the two groups.

摘要

我们旨在评估年龄和症状持续时间对接受单节段显微镜下颈椎前路椎间盘切除融合术(ACDF)治疗的神经根型颈椎病(CSR)患者手术效果的影响。我们回顾性评估了伊玛目·礼萨医院骨科的68例患者(48例女性和20例男性),平均年龄为41.2±4.3岁(年龄范围为24至72岁)。他们接受了31.25±4.1个月(范围为25至65个月)的随访。在术前和末次随访时,通过视觉模拟量表(VAS)和颈部功能障碍指数(NDI)问卷评估疼痛和功能障碍情况。最终根据奥多姆标准评估功能结局。手术可使疼痛和功能障碍从术前的6.2±1.4和22.2±6.2分别显著改善至末次随访时的3.5±2.0和8.7±5.2(1 - 21)。89.7%的患者获得了满意的结果。症状持续时间超过和少于六个月对手术效果均无影响,但结果显示,尽管两组疼痛改善情况相似,但年龄大于45岁患者的NDI改善具有统计学显著差异(P = 0.032)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ce5/4437266/a777f5fc9f85/NEUROSCIENCE2014-808596.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ce5/4437266/84d97ecb5896/NEUROSCIENCE2014-808596.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ce5/4437266/a777f5fc9f85/NEUROSCIENCE2014-808596.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ce5/4437266/84d97ecb5896/NEUROSCIENCE2014-808596.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ce5/4437266/a777f5fc9f85/NEUROSCIENCE2014-808596.002.jpg

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The impact of menopause on bone fusion after the single-level anterior cervical discectomy and fusion.绝经对单节段颈椎前路椎间盘切除融合术后骨融合的影响。
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