• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Vascular protective effects of Angiotensin Receptor Blockers: Beyond Blood pressure.血管紧张素受体阻滞剂的血管保护作用：超越血压
Receptors Clin Investig. 2015;2(3). doi: 10.14800/rci.774.
2
Candesartan stimulates reparative angiogenesis in ischemic retinopathy model: role of hemeoxygenase-1 (HO-1).坎地沙坦刺激缺血性视网膜病变模型中的修复性血管生成：血红素加氧酶-1（HO-1）的作用。
Angiogenesis. 2015 Apr;18(2):137-50. doi: 10.1007/s10456-014-9451-4. Epub 2014 Nov 25.
3
Effect of angiotensin II type 1 receptor blocker, candesartan, and beta 1 adrenoceptor blocker, atenolol, on brain damage in ischemic stroke.血管紧张素II 1型受体阻滞剂坎地沙坦和β1肾上腺素能受体阻滞剂阿替洛尔对缺血性脑卒中脑损伤的影响。
Acta Physiol Hung. 2010 Jun;97(2):159-71. doi: 10.1556/APhysiol.97.2010.2.2.
4
Candesartan, an angiotensin II type 1 receptor antagonist, inhibits pathological retinal neovascularization by downregulating VEGF receptor-2 expression.坎地沙坦，血管紧张素 II 型 1 型受体拮抗剂，通过下调 VEGF 受体-2 的表达抑制病理性视网膜新生血管形成。
Eur J Pharmacol. 2012 Jun 15;685(1-3):8-14. doi: 10.1016/j.ejphar.2012.04.017. Epub 2012 Apr 20.
5
Brain-Derived Neurotrophic Factor Knockdown Blocks the Angiogenic and Protective Effects of Angiotensin Modulation After Experimental Stroke.脑源性神经营养因子基因敲低可阻断实验性中风后血管紧张素调节的血管生成和保护作用。
Mol Neurobiol. 2017 Jan;54(1):661-670. doi: 10.1007/s12035-015-9675-3. Epub 2016 Jan 12.
6
Negative regulation of VEGF-induced vascular leakage by blockade of angiotensin II type 1 receptor.通过阻断1型血管紧张素II受体对血管内皮生长因子诱导的血管渗漏进行负调控。
Arterioscler Thromb Vasc Biol. 2006 Dec;26(12):2673-80. doi: 10.1161/01.ATV.0000245821.77155.c3. Epub 2006 Sep 14.
7
Serum MCP-1 and VEGF levels are not affected by inhibition of the renin-angiotensin system in patients with acute myocardial infarction.
Cardiovasc Drugs Ther. 2003 May;17(3):249-55. doi: 10.1023/a:1026128308440.
8
Angiotensin receptor blockers following acute stroke.急性卒中后的血管紧张素受体阻滞剂
Expert Rev Cardiovasc Ther. 2011 Jun;9(6):691-6. doi: 10.1586/erc.11.60.
9
Effects of an ARB on endothelial progenitor cell function and cardiovascular oxidation in hypertension.一种血管紧张素受体阻滞剂对高血压患者内皮祖细胞功能及心血管氧化的影响。
Am J Hypertens. 2008 Jan;21(1):72-7. doi: 10.1038/ajh.2007.5.
10
Stroke prevention with the angiotensin II type 1-receptor blocker candesartan in elderly patients with isolated systolic hypertension: the Study on Cognition and Prognosis in the Elderly (SCOPE).血管紧张素II 1型受体阻滞剂坎地沙坦用于老年单纯收缩期高血压患者的卒中预防：老年认知与预后研究（SCOPE）
J Am Coll Cardiol. 2004 Sep 15;44(6):1175-80. doi: 10.1016/j.jacc.2004.06.034.

引用本文的文献

1
Cross-sectional association between plasma aldosterone concentration and cognitive performance by mini-mental state examination in community dwellers.社区居民中血浆醛固酮浓度与简易精神状态检查认知表现之间的横断面关联。
Front Nutr. 2025 Feb 6;12:1519644. doi: 10.3389/fnut.2025.1519644. eCollection 2025.
2
Pharmacogenomics Informs Cardiovascular Pharmacotherapy.药物基因组学指导心血管药物治疗。
Methods Mol Biol. 2022;2547:201-240. doi: 10.1007/978-1-0716-2573-6_9.
3
Positive Association Between Plasma Aldosterone Concentration and White Matter Lesions in Patients With Hypertension.血浆醛固酮浓度与高血压患者脑白质病变呈正相关。
Front Endocrinol (Lausanne). 2021 Nov 18;12:753074. doi: 10.3389/fendo.2021.753074. eCollection 2021.
4
Within the Brain: The Renin Angiotensin System.脑内肾素血管紧张素系统。
Int J Mol Sci. 2018 Mar 15;19(3):876. doi: 10.3390/ijms19030876.
5
Ameliorative Effect of Coenzyme Q10 and/or Candesartan on Carboplatin-Induced Nephrotoxicity: Roles of Apoptosis, Transforming Growth Factor-Β1, Nuclear Factor Kappa-B And The Nrf2/HO-1 Pathway.辅酶Q10和/或坎地沙坦对卡铂诱导的肾毒性的改善作用：细胞凋亡、转化生长因子-β1、核因子κB及Nrf2/HO-1信号通路的作用
Asian Pac J Cancer Prev. 2017 Jun 25;18(6):1629-1636. doi: 10.22034/APJCP.2017.18.6.1629.

本文引用的文献

1
Nitric oxide is an important regulator of heme oxygenase-1 expression in the lipopolysaccharide and interferon-γ-treated murine macrophage-like cell line J774.1/JA-4.一氧化氮是脂多糖和干扰素-γ处理的小鼠巨噬细胞样细胞系J774.1/JA-4中血红素加氧酶-1表达的重要调节因子。
Biol Pharm Bull. 2015;38(1):7-16. doi: 10.1248/bpb.b14-00405.
2
Tipping off endothelial tubes: nitric oxide drives tip cells.提示内皮管形成：一氧化氮驱动顶端细胞。
Angiogenesis. 2015 Apr;18(2):175-89. doi: 10.1007/s10456-014-9455-0. Epub 2014 Dec 16.
3
Candesartan stimulates reparative angiogenesis in ischemic retinopathy model: role of hemeoxygenase-1 (HO-1).坎地沙坦刺激缺血性视网膜病变模型中的修复性血管生成：血红素加氧酶-1（HO-1）的作用。
Angiogenesis. 2015 Apr;18(2):137-50. doi: 10.1007/s10456-014-9451-4. Epub 2014 Nov 25.
4
Deletion of thioredoxin interacting protein (TXNIP) augments hyperoxia-induced vaso-obliteration in a mouse model of oxygen induced-retinopathy.硫氧还蛋白相互作用蛋白（TXNIP）的缺失加剧了氧诱导性视网膜病变小鼠模型中高氧诱导的血管闭塞。
PLoS One. 2014 Oct 16;9(10):e110388. doi: 10.1371/journal.pone.0110388. eCollection 2014.
5
Compound 21 is pro-angiogenic in the brain and results in sustained recovery after ischemic stroke.化合物21在大脑中具有促血管生成作用，并能在缺血性中风后带来持续恢复。
J Hypertens. 2015 Jan;33(1):170-80. doi: 10.1097/HJH.0000000000000364.
6
Role of matrix metalloproteinase activity in the neurovascular protective effects of Angiotensin antagonism.基质金属蛋白酶活性在血管紧张素拮抗的神经血管保护作用中的作用。
Stroke Res Treat. 2014;2014:560491. doi: 10.1155/2014/560491. Epub 2014 Jul 24.
7
Low-dose candesartan enhances molecular mediators of neuroplasticity and subsequent functional recovery after ischemic stroke in rats.低剂量坎地沙坦可增强大鼠缺血性中风后神经可塑性的分子介质及随后的功能恢复。
Mol Neurobiol. 2015;51(3):1542-53. doi: 10.1007/s12035-014-8830-6. Epub 2014 Aug 2.
8
Candesartan induces a prolonged proangiogenic effect and augments endothelium-mediated neuroprotection after oxygen and glucose deprivation: role of vascular endothelial growth factors A and B.坎地沙坦诱导长时间的促血管生成作用，并增强缺氧和葡萄糖剥夺后的内皮细胞介导的神经保护作用：血管内皮生长因子 A 和 B 的作用。
J Pharmacol Exp Ther. 2014 Jun;349(3):444-57. doi: 10.1124/jpet.113.212613. Epub 2014 Mar 28.
9
Direct stimulation of angiotensin II type 2 receptor initiated after stroke ameliorates ischemic brain damage.中风后启动的对血管紧张素 II 2 型受体的直接刺激可改善缺血性脑损伤。
Am J Hypertens. 2014 Aug;27(8):1036-44. doi: 10.1093/ajh/hpu015. Epub 2014 Feb 26.
10
Azilsartan, an angiotensin II type 1 receptor blocker, restores endothelial function by reducing vascular inflammation and by increasing the phosphorylation ratio Ser(1177)/Thr(497) of endothelial nitric oxide synthase in diabetic mice.阿齐沙坦，一种血管紧张素II 1型受体阻滞剂，通过减轻血管炎症和提高糖尿病小鼠内皮型一氧化氮合酶的Ser(1177)/Thr(497)磷酸化比率来恢复内皮功能。
Cardiovasc Diabetol. 2014 Jan 31;13:30. doi: 10.1186/1475-2840-13-30.

Vascular protective effects of Angiotensin Receptor Blockers: Beyond Blood pressure.

作者信息

Artham Sandeep, Fouda Abdelrahman Y, El-Remessy Azza B, Fagan Susan C

机构信息

Program in Clinical and Experimental Therapeutics, University of Georgia College of Pharmacy, and Georgia Regents University, Charlie Norwood VA Medical Center, Augusta, GA, USA.

出版信息

Receptors Clin Investig. 2015;2(3). doi: 10.14800/rci.774.

DOI:10.14800/rci.774
PMID:26317114
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4548973/
Abstract
摘要