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与腹腔镜袖状胃切除术患者相比,腹腔镜Roux-en-Y胃旁路手术患者再次手术的终生风险增加。

Laparoscopic Roux-en-Y gastric bypass patients have an increased lifetime risk of repeat operations when compared to laparoscopic sleeve gastrectomy patients.

作者信息

Zak Yulia, Petrusa Emil, Gee Denise W

机构信息

Massachusetts General Hospital, 15 Parkman Street, WAC 460, Boston, MA, 02114, USA.

MGH Learning Lab, Massachusetts General Hospital, 3 Hawthorne Place, Suite 105, Boston, MA, 02114, USA.

出版信息

Surg Endosc. 2016 May;30(5):1833-8. doi: 10.1007/s00464-015-4466-5. Epub 2015 Aug 29.

Abstract

BACKGROUND

Although long-term data have been published on the complications after laparoscopic Roux-en-Y gastric bypass (LRYGB), laparoscopic sleeve gastrectomy (LSG) is a relatively new procedure without a well-established long-term procedure-related morbidity profile. Our aim was to compare the 6-year data on re-operations occurring after and related to LRYGB versus LSG at a large academic bariatric center.

METHODS

Retrospective review of all the bariatric procedures at the Massachusetts General Hospital between 2009 and 2014.

RESULTS

A total of 934 LRYGB and 553 LSG were performed. There were no significant differences in the gender, age, or BMI of the patients at the time of their index operations (p > 0.05 for all). A higher percentage of LRYGB patients required cholecystectomy as compared to LSG patients (5 vs. 2 %, X (2) = 8.63, p < 0.01). There was also a significant difference in the proportion of patients requiring re-operations for other reasons following LRYGB as compared to LSG (6.9 vs. 0.9 %, X (2) = 27.8, p < 0.01). A total of 32.8 % of these bypass patients underwent more than one re-operation, with a relative risk of 11.5 (95 % CI 4.69-28.5) as compared to those undergoing SG. A total of 9.3 % of secondary operations occurred at a mean of 1 month after the LRYGB for functional obstruction, with most of these cases related to a technical error. Other re-operations occurred in a delayed fashion, without a clearly identifiable intra-abdominal source in 22.2 %, due to adhesive bowel obstruction in 17.6 %, and internal hernia in 15.7 %. Non-healing ulcers and intussusception were responsible for a small percentage of re-operations (3.7 and 2.8 %).

CONCLUSIONS

SG is associated with a relatively low rate of re-operations, while patients after LRYGB are at a significant long-term risk for multiple operative procedures.

摘要

背景

尽管已经发表了关于腹腔镜Roux-en-Y胃旁路术(LRYGB)后并发症的长期数据,但腹腔镜袖状胃切除术(LSG)是一种相对较新的手术,其长期手术相关发病率尚无完善的资料。我们的目的是比较在一家大型学术性减肥中心,LRYGB与LSG术后6年再次手术及相关情况的数据。

方法

回顾性分析2009年至2014年期间麻省总医院所有的减肥手术。

结果

共进行了934例LRYGB和553例LSG手术。初次手术时患者的性别、年龄或体重指数(BMI)无显著差异(所有p>0.05)。与LSG患者相比,LRYGB患者需要行胆囊切除术的比例更高(5%对2%,X(2)=8.63,p<0.01)。与LSG相比,LRYGB术后因其他原因需要再次手术的患者比例也有显著差异(6.9%对0.9%,X(2)=27.8,p<0.01)。这些胃旁路手术患者中共有32.8%接受了不止一次再次手术,与接受袖状胃切除术的患者相比,相对风险为11.5(95%可信区间4.69-28.5)。LRYGB术后9.3%的二次手术平均发生在术后1个月,原因是功能性梗阻,其中大多数病例与技术失误有关。其他再次手术发生时间较晚,22.2%无明确可识别的腹腔内病因,17.6%是由于粘连性肠梗阻,15.7%是由于内疝。非愈合性溃疡和肠套叠导致的再次手术比例较小(3.7%和2.8%)。

结论

LSG的再次手术率相对较低,而LRYGB术后患者面临多次手术的显著长期风险。

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