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对于初次全膝关节置换术,氮化钛铌膝关节植入物并不逊色于铬钴部件。

Titanium niobium nitride knee implants are not inferior to chrome cobalt components for primary total knee arthroplasty.

作者信息

Thienpont Emmanuel

机构信息

Department of Orthopedic Surgery, University Hospital Saint Luc, Av. Hippocrate 10, 1200, Brussels, Belgium.

出版信息

Arch Orthop Trauma Surg. 2015 Dec;135(12):1749-54. doi: 10.1007/s00402-015-2320-9. Epub 2015 Aug 29.

Abstract

BACKGROUND

Metal allergy in total knee arthroplasty (TKA) is still a controversial topic. Oxinium, ceramic or titanium niobium nitride (TiNbN) coated implants are available for some knee systems. The hypothesis of this study was that the use of TiNbN-coated components would not lead to inferior results compared to conventional implants and that none of the allergic patients receiving TiNbN-coated implants would require revision for metal allergy.

MATERIALS AND METHODS

This study was a retrospective, 2 to 1 matched pairs study with 40 titanium niobium nitride-coated TKA compared with 80 conventional cobalt chrome implants. No demographic differences between these groups were observed. The mean follow-up for this study was 2 years.

RESULTS

No differences in clinical, radiological, or patient-reported outcome measurements were observed between the two groups. No patients have been revised at this short- to medium-term outcome evaluation.

DISCUSSION

Metal allergy leading to contact or systemic dermatitis is especially linked to chrome and cobalt allergy. Nickel allergy because of knee implants rarely gives cutaneous symptoms, but could potentially lead to peri-prosthetic osteolysis and loosening. The use of titanium niobium nitride implants in case of a positive history of metal allergy could avoid this devastating complication.

CONCLUSION

The use of titanium niobium nitride-coated implants for primary knee osteoarthritis shows similar clinical and radiological outcomes as conventional TKA without revision for loosening at short- to medium-term follow-up. Level of evidence Level IV study.

摘要

背景

全膝关节置换术(TKA)中的金属过敏仍然是一个有争议的话题。对于一些膝关节系统,有含钽铌氧化物、陶瓷或氮化钛铌(TiNbN)涂层的植入物可供选择。本研究的假设是,与传统植入物相比,使用TiNbN涂层组件不会导致较差的结果,并且接受TiNbN涂层植入物的过敏患者中没有人会因金属过敏而需要翻修。

材料与方法

本研究是一项回顾性的2:1配对研究,将40例TiNbN涂层的TKA与80例传统钴铬合金植入物进行比较。两组之间未观察到人口统计学差异。本研究的平均随访时间为2年。

结果

两组在临床、放射学或患者报告的结局测量方面均未观察到差异。在这个短期至中期结局评估中,没有患者进行翻修。

讨论

导致接触性皮炎或全身性皮肤炎的金属过敏尤其与铬和钴过敏有关。膝关节植入物引起的镍过敏很少出现皮肤症状,但可能导致假体周围骨溶解和松动。对于有金属过敏史的患者,使用氮化钛铌植入物可以避免这种毁灭性的并发症。

结论

对于原发性膝关节骨关节炎,使用TiNbN涂层植入物在短期至中期随访中显示出与传统TKA相似的临床和放射学结果,且无需因松动而进行翻修。证据级别:IV级研究。

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