May S J, Blackwell C C, Weir D M
Department of Bacteriology, Medical School, University of Edinburgh, U.K.
FEMS Microbiol Immunol. 1989 Jun;1(6-7):407-9. doi: 10.1111/j.1574-6968.1989.tb02429.x.
This study tested the hypothesis that the Lewis a blood group antigen found predominantly on the cells of non-secretors might be one of the receptors for Candida species. Binding of strain 3118C to epithelial cells from either secretor or non-secretor donors was not inhibited by treating the cells with anti-Lewis a or anti-Lewis b antisera. Binding of strain 3091 to non-secretor cells was inhibited by pretreating the cells with anti-Lewis a, but this was not observed for secretor cells. The results suggest that Lewis a might be one of the receptors for some yeast strains.
主要存在于非分泌型个体细胞上的Lewis a血型抗原可能是念珠菌属的受体之一。用抗Lewis a或抗Lewis b抗血清处理细胞，并未抑制3118C菌株与分泌型或非分泌型供体的上皮细胞的结合。用抗Lewis a预处理细胞可抑制3091菌株与非分泌型细胞的结合，但在分泌型细胞中未观察到这种情况。结果表明，Lewis a可能是某些酵母菌株的受体之一。
