Hobstová J, Hancil J, Danes L
Cas Lek Cesk. 1989 Dec 8;128(50):1587-90.
In 1986 in the CSR 978 cases of acute meningoencephalitis were notified, incl. 184 in the capital. In a group of 129 patients aged 1 to 63 years hospitalized at the First Clinic for Infectious Diseases in Prague-Bulovka (Paediatric Faculty Charles University) in 1986 the authors investigated the clinical course of acute meningoencephalitis in relation to the causal agent of the disease. The aetiological agent was assessed by isolation from cerebrospinal fluid or by isolation from faeces with the corresponding antibody response, or by serological examination only. In children under 15 years of age the etiological agent was assessed in 36%, in adults in 65%. In the investigated group, contrary to previous years (3), tick-borne encephalitis was involved which accounted for the majority of severe cases of the disease. The severe clinical course, manifested at first by symptoms of cerebral oedema with impaired consciousness, is more frequent with advancing age. In adults tick-borne encephalitis had a severe course in one third of the patients. In the other age groups the development was favourable, in particular in the group of children aged 4-10 years. As compared with previous years, there was no fatal case, no permanent paresis as a complication of the disease (2).
1986年，捷克斯洛伐克社会主义共和国通报了978例急性脑膜脑炎病例，其中包括首都的184例。1986年，作者对在布拉格-布洛夫卡第一传染病诊所（查理大学儿科系）住院的129例年龄在1至63岁的患者进行了研究，探讨急性脑膜脑炎的临床病程与病因的关系。病因通过从脑脊液中分离病原体、从粪便中分离病原体并结合相应的抗体反应或仅通过血清学检查来评估。15岁以下儿童的病原体评估率为36%，成人的评估率为65%。与前几年不同（3），该研究组涉及蜱传脑炎，该病占该疾病严重病例的大多数。严重的临床病程起初表现为脑水肿伴意识障碍症状，且随着年龄增长更为常见。在成人中，三分之一的蜱传脑炎患者病程严重。在其他年龄组中病情发展良好，尤其是在4至10岁的儿童组。与前几年相比，没有出现死亡病例，也没有因该病并发症导致永久性麻痹的情况（2）。
