Romanello C, Capizzi A, Pocecco M, Cristofori G
Clinica Pediatrica - Istituto per l'Infanzia Burlo Garofolo, Trieste, Italia.
Pediatr Med Chir. 1989 Jan-Feb;11(1):21-5.
Twenty patients with viral encephalitis were studied retrospectively. Among these, in 2 cases, it was possible to formulate the diagnosis of encephalitis with viral replication by herpes virus on the basis of finding of cerebrospinal fluid IgM, serum and/or cerebrospinal fluid specific antibody rate movement and TC-scan necrotic lesions in typical sites. In 18 of 20 patients it was formulated the generic diagnosis of encephalitis without evidence of viral replication. Among these last 18 patients, 7 were considered affected by post-infective encephalitis on the basis of the anamnestic finding of the causing disease within 30 days from the appearance of the first symptoms. Into the 11 other the etiology was anamnestically hidden. The outcome was essentially favourable in the considered cases (16/20 complete recoveries). Poor outcome factors were considered the presence of herpetic infection and TC-scan alterations into the group of encephalitis without evidence of viral replication in association of anamnestic finding of measles.
对20例病毒性脑炎患者进行了回顾性研究。其中，2例根据脑脊液IgM、血清和/或脑脊液特异性抗体率变化以及典型部位的CT扫描坏死性病变，确诊为疱疹病毒引起的伴有病毒复制的脑炎。20例患者中有18例确诊为无病毒复制证据的一般性脑炎。在这最后18例患者中，7例根据首次出现症状后30天内发现致病疾病的既往史，被认为患有感染后脑炎。在另外11例中，病因在既往史中未明确。在所研究的病例中，预后基本良好（20例中有16例完全康复）。不良预后因素被认为是在无病毒复制证据的脑炎组中存在疱疹感染和CT扫描改变，同时伴有麻疹的既往史。
