Lenaeus Michael J, Hirschmann Jan
Department of General Internal Medicine, University of Washington Medical Center, 1959 Northeast Pacific Street, Box 356429, Seattle, WA 98195-6429, USA.
Department of General Internal Medicine, Puget Sound VA Medical Center, University of Washington School of Medicine, 1660 South Columbian Way, Seattle, WA 98108, USA.
Med Clin North Am. 2015 Sep;99(5):953-67. doi: 10.1016/j.mcna.2015.05.007.
Obstructive lung disease includes asthma and chronic obstructive pulmonary disease (COPD). Because a previous issue of Medical Clinics of North America (2012;96[4]) was devoted to COPD, this article focuses on asthma in adults, and addresses some topics about COPD not addressed previously. Asthma is a heterogeneous disease marked by variable airflow obstruction and bronchial hyperreactivity. Onset is most common in early childhood, although many people develop asthma later in life. Adult-onset asthma presents a particular challenge in the primary care clinic because of incomplete understanding of the disorder, underreporting of symptoms, underdiagnosis, inadequate treatment, and high rate of comorbidity.
阻塞性肺病包括哮喘和慢性阻塞性肺疾病(COPD)。由于《北美医学临床》之前的一期(2012年;96[4])专门讨论了COPD,本文重点关注成人哮喘,并探讨一些之前未涉及的关于COPD的话题。哮喘是一种异质性疾病,其特征为气流受限和支气管高反应性可变。虽然许多人在生命后期才患上哮喘,但发病最常见于儿童早期。由于对该疾病的认识不全面、症状报告不足、诊断不足、治疗不充分以及合并症发生率高,成人发病的哮喘在基层医疗诊所中面临着特殊的挑战。