Merali N, Almeida R A R, Hussain A
King's College Hospital NHS Foundation Trust, London, United Kingdom; Bart's Cancer Institute, MSc Surgical Skills & Science, London, United Kingdom.
Hospital Maternidade Sao Jose-Colatina, ES, Brazil; Bart's Cancer Institute, MSc Surgical Skills & Science, London, United Kingdom.
Int J Surg Case Rep. 2015;15:99-102. doi: 10.1016/j.ijscr.2015.07.034. Epub 2015 Aug 1.
We present a case on conservative management of salvaging the mesh in an immunocompromised morbidly obese patient, who developed a synergistic gangrene infection following a primary open mesh repair of an incisional hernia.
Our patient presented with a surgical wound infection, comorbidities were Chronic Lymphoblastic Leukemia (CLL), Body Mass Index (BMI) of 50, hypertension and diet controlled type-2 diabetes. In surgery, wide necrotic wound debridement, early and repetitive wound drainages with the use of a large pore polypropylene mesh and a detailed surgical follow up was required. High dose intravenous broad-spectrum antibiotic treatment and Negative Pressure Wound Therapy (NPWT) was administrated in combination with adopting a multidisciplinary approach was key to our success.
Stoppa Re et al. complied a series of 360 ventral hernia mesh repairs reporting an infection rate of 12% that were managed conservatively. However, our selective case is unique within current literature, being the first to illustrate mesh salvage in a morbid obese patient with CLL. Recent modifications in mesh morphology, such as lower density, wide pores, and lighter weight has led to considerable improvements regarding infection avoidance.
This case has demonstrated how a planned multidisciplinary action can produce prosperous results in a severely obese immunocompromised patient with an SSI, following an incisional hernia repair.
我们报告一例免疫功能低下的病态肥胖患者切口疝初次开放补片修补术后发生协同性坏疽感染,对其补片进行保守治疗的病例。
我们的患者出现手术伤口感染,合并症有慢性淋巴细胞白血病(CLL)、体重指数(BMI)为50、高血压以及饮食控制的2型糖尿病。手术中,需要进行广泛的坏死伤口清创、早期及反复的伤口引流,使用大孔隙聚丙烯补片并进行详细的手术随访。大剂量静脉注射广谱抗生素治疗和负压伤口治疗(NPWT),并采用多学科方法是我们成功的关键。
Stoppa Re等人汇总了一系列360例腹疝补片修补术,报告保守治疗的感染率为12%。然而,我们的这个特殊病例在当前文献中是独一无二的,是首例说明在患有CLL的病态肥胖患者中挽救补片的病例。补片形态的最新改进,如低密度、宽孔隙和更轻的重量,在避免感染方面有了显著改善。
该病例表明,在切口疝修补术后,对于患有手术部位感染(SSI)的严重肥胖免疫功能低下患者,有计划的多学科行动如何能产生良好的结果。