Hu Xiao-Xiao, Su Yue-Ting, Ma Yun-Wei, Zhan Xin-Qi, Zheng Hong, Jiang Yun-Bao
Department of Chemistry, College of Chemistry and Chemical Engineering, and the MOE Key Laboratory of Physical Laboratory of Spectrochemical Analysis & Instrumentation, Xiamen University, Xiamen, 361005, China.
Chem Commun (Camb). 2015 Oct 21;51(82):15118-21. doi: 10.1039/c5cc04630k.
A near infrared probe for sensitive colorimetric and fluorimetric detection of nerve agent mimics, DCP and DCNP, was reported based on the activation of a carboxylic acid group by the mimics to conduct an intramolecular amidation reaction in the heptamethine chromophore, where its absorption or excitation maximum wavelength could be greatly red-shifted by attenuating the electron-donating ability of the amine group in the bridgehead site of heptamethine cyanine.
基于神经毒剂模拟物（二氯磷酸酯和二氯硝基磷酸酯）对羧酸基团的活化作用，在七甲川发色团中进行分子内酰胺化反应，报道了一种用于灵敏比色和荧光检测神经毒剂模拟物的近红外探针。在此过程中，通过减弱七甲川花菁桥头位点胺基的给电子能力，其吸收或激发最大波长可发生显著红移。
