Hazards Monitoring Bionano Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, South Korea.
Department of Polymer Engineering, Graduate School, Chonnam National University, Gwangju 61186, South Korea.
Sci Rep. 2016 Sep 21;6:33724. doi: 10.1038/srep33724.
Organophosphates are powerful inhibitors of acetylcholinesterase, which is critical to nerve function. Despite continuous research for detecting the highly toxic organophosphates, a new and improved methodology is still needed. Herein we demonstrate simple-to-fabricate chemiresistive gas sensors using conducting-polymer polypyrrole (PPy) nanotube transducers, which are chemically specific and capable of recognizing sub-ppb concentrations (ca. 0.5 ppb) of dimethyl methylphosphonate (DMMP), a simulant of nerve agent sarin. Interestingly, the introduction of carboxylic groups on the surface of PPy nanotube transistors resulted in enhanced sensitivity to DMMP via intermolecular hydrogen bonding. Furthermore, it was found that the sensitivity of the nanotube transducer depended on the degree of the carboxylic group introduced. Finally, a sensor array composed of 5 different transducers including the carboxylated nanotubes exhibited excellent selectivity to DMMP in 16 vapor species.
有机磷酸酯是乙酰胆碱酯酶的强效抑制剂，而乙酰胆碱酯酶对神经功能至关重要。尽管人们一直在研究用于检测高毒性有机磷酸酯的方法，但仍需要新的、改进的方法。在此，我们展示了使用导电聚合物聚吡咯（PPy）纳米管换能器制造简单的电阻式气体传感器，该传感器具有化学特异性，能够识别亚 ppb 浓度（约 0.5 ppb）的二甲甲基膦酸酯（DMMP），这是沙林神经毒剂的模拟物。有趣的是，在 PPy 纳米管晶体管表面引入羧酸基团会通过分子间氢键增强对 DMMP 的敏感性。此外，研究还发现，纳米管换能器的灵敏度取决于引入的羧酸基团的程度。最后，由 5 个不同的换能器组成的传感器阵列，包括羧化纳米管，对 16 种蒸气物种中的 DMMP 表现出优异的选择性。
