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乳腺癌治疗疗效的分子标志物进展

Molecular markers' progress of breast cancer treatment efficacy.

作者信息

Wang Dan, Xu Jingwei, Shi Guang, Yin Guanghao

机构信息

Department of Breast Surgery, The Second Hospital of Jilin University, Changchun City, Jilin Province 130041, China.

出版信息

J Cancer Res Ther. 2015 Aug;11 Suppl 1:C11-5. doi: 10.4103/0973-1482.163832.

Abstract

Breast cancer is a famous malignant tumor which is caused by varieties of mutation in multiple genes. In order to detect breast cancer in an earlier time and take appropriate treatment which includes  predicting treatment efficacy, we need a more accurate method of discovering the occurrence of breast cancer. With the development of molecular biology and biological detection technologies continue to emerge, molecular markers of breast cancer have gaining more and more widespread attention, and combining with molecular markers of breast cancer in clinical characteristic of individual treatment for breast cancer has become possible. In this paper, we will focus on the advances about molecular markers associated with treatment efficacy in recent years.

摘要

乳腺癌是一种著名的恶性肿瘤,它由多个基因的多种突变引起。为了更早地检测乳腺癌并采取适当的治疗措施,包括预测治疗效果,我们需要一种更准确的方法来发现乳腺癌的发生。随着分子生物学的发展以及生物检测技术不断涌现,乳腺癌的分子标志物越来越受到广泛关注,并且将乳腺癌分子标志物与个体治疗的临床特征相结合用于乳腺癌治疗已成为可能。在本文中,我们将重点关注近年来与治疗效果相关的分子标志物的研究进展。

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