钯催化炔烃插入环状二芳基碘鎓盐：直接合成多取代菲的方法。
Pd catalyzed insertion of alkynes into cyclic diaryliodoniums: a direct access to multi-substituted phenanthrenes.
作者信息
Wu Yongcheng, Wu Fuhai, Zhu Daqian, Luo Bingling, Wang Haiwen, Hu Yumin, Wen Shijun, Huang Peng
机构信息
Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, 651 Dongfeng East Road, Guangzhou 510060, China.
出版信息
Org Biomol Chem. 2015 Nov 7;13(41):10386-91. doi: 10.1039/c5ob01597a.
Cyclic diaryliodoniums remain unexplored compared to linear iodoniums. In our current work, internal alkynes were for the first time applied to react with cyclic iodoniums, catalyzed by Pd, resulting in a [4 + 2] benzannulation. Our work offers a new strategy to synthesize multi-substituted phenanthrene derivatives which are not easily accessed by conventional methods.
与线性碘鎓盐相比，环状二芳基碘鎓盐尚未得到充分研究。在我们目前的工作中，首次将内部炔烃用于与环状碘鎓盐在钯催化下反应，从而实现[4 + 2]苯并环化反应。我们的工作为合成多取代菲衍生物提供了一种新策略，而这些衍生物用传统方法难以获得。
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